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半乳糖凝集素-3在急性冠状动脉综合征和稳定性冠心病诊断中的应用 被引量:6

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摘要 全球每年约有1900万人死于心脏疾病,其中急性冠脉综合征(acutecoronarysyndrome,ACS)为最主要的临床类型。冠状动脉粥样硬化斑块的不稳定性是临床发生ACS的主要病理基础,而炎症在动脉粥样硬化斑块从稳定向不稳定状态转化的过程中起着至关重要的作用。目前,应用最广范、最成熟的心脏标志物包括肌红蛋白、心脏肌钙蛋白、CK—MB、CRP以及BNP、Pro.BNP等。
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2012年第2期160-163,共4页 Chinese Journal of Emergency Medicine
基金 基金项目:浙江省医药卫生科技计划项目(2010KYA090)
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  • 1Lucas AD,Greaves DR.Atherosclerosis:role of chemokines and macrophages[J].Expert Rev Mol Med,2001,3(25):1-18.
  • 2Glass CK,Witztum JL.Atherosclrosis the road ahead[J].Cell,2001,104(4):503-516.
  • 3Ozaki K,Inoue K,Sato H,et al.Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro[J].Nature,2004,429(6987):72-75.
  • 4Chiariotti L,Salvatore P.Frunzio R,et al.Galectin gene:regulation of expression[J].Glycoconjugate J,2004,19(7/9):441-449.
  • 5Dumic J,Dabelic S,Flogel M.Galectin-3:an open-ended story[J].Biochim Biophys Acta,2006,1760(4):616-635.
  • 6Stillman BN,Hsu DK,Pang M,et al.Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death[J].J Immunol,2006,176(2):778-789.
  • 7Hammerer-Lercher A,Neubauer E,Muller S,et al.Head-to-head comparison of N-terminal pro-brain natriuretic peptide,brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction[J].Clin Chim Acta,2001,310(2):193-197.
  • 8Rao SP,Wang Z,Zuberi RI,et al.Galectin-3 functions as an adhesion modecule to support eosinophil rolling and adhesion under conditions of flow[J].J Immunol,2007,179(11):7800-7807.
  • 9Muller S,Schaffer T,Flogerzi B,et al.Galectin-3 modulates T cell activity and is reduced in the inflamed intestinal epithelium in IBD[J].Inflamm Bowel Dis,2006,12(7):588-597.
  • 10Zhu W,Sallo H,Nagai R,et al.The role of Galectin-3 in endocytosis of advanced glycation end products and modified low density lipopro-teins[J].Biochem Biophys Res Commun,2001,280(4):1183-1188.

同被引文献53

  • 1Yang RY, Rabinovich GA, Liu FT. Galectins : structure, func tion and therapeutic potential. Expert Rev Mol Med, 2008, 10:e17.
  • 2Dumic J, Dabelic S, Flogel M. Galectins: an open ended story. Biochim Biophys Acta, 2006,1760 :616- 635.
  • 3Eude-Le P,Gendronneau G,Dang T,et al. Genetic assessment of the importance of galectin 3 in cancer initiation, progres sion, and dissemination in mice. Glycobiology, 2009, 19 : 68 -75.
  • 4Jiang JX, Chen X, Hsu DK, et al. Galectin 3 modulates phago cytosis induced stellate cell activation and liver fibrosis in vi Liver Physiol, 2012,302 : G439-G446.
  • 5Okamura l)M,Pasichnyk K,Lopez Guisa JM,et al. Galeetin 3 preserves renal tubules and modulates extracellular matrix re modeling in progressive fibrosis. Am J Physiol Renal Pbysiol, 2011,300:F245- F253.
  • 6Felker GM,Fiuzat M,Shaw LK,et al. Galectin 3 in ambulato ry patients with heart failure: results from the HF-ACTION study.Cire Heart Fail,2012,5:72- 78.
  • 7de Boer RA, Lok DJ, Jaarsma T, et al. Predictive value of plasma galectin 3 levels in heart failure with reduced and pre served ejection fraction. Ann Med, 2011,43 : 60 -68.
  • 8Tang WH, Shreatha K, Shao Z, et al. Usefulness of plasma galectin 3 levels in systolic heart failure to predict renal insuf ficiency and survival. Am J Cardiol, 2011,108 : 385- 390.
  • 9de Boer RA, Voors AA, Muntendam P, et al. Galectin-3 : a no vel mediator of heart failure development and progression. Eur J Heart Fail,2009,11:811- 817.
  • 10Anand IS,Rector TS,Kuskowski M, et al. Baseline and serial measurements of galectin 3 in patients with heart failure: rela tionship to prognosis and effect of treatment with valsanan in the Val HEFT. EurJ Heart Fail,2013,15:511- 518.

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