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系统性红斑狼疮血脂代谢异常影响因素 被引量：2

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摘要 系统性红斑狼疮(SLE)是一种涉及多因素、累及多器官的系统性自身免疫性疾病。国内外实验研究均表明SLE患者存在不同程度的血脂代谢异常。血脂代谢异常会引起动脉粥样硬化(AS),导致心、脑、肾等多脏器的各种并发症,直接影响自身疾病的发生、发展及预后。
作者 李蓉 蔡辉
机构地区 南京军区南京总医院中西医结合科
出处 《江苏医药》 CAS CSCD 北大核心 2012年第3期329-332,共4页 Jiangsu Medical Journal
关键词 系统性红斑狼疮 血脂代谢异常 影响因素 系统性自身免疫性疾病 动脉粥样硬化 SLE患者 实验研究 自身疾病
分类号 R593 [医药卫生—内科学]
  • 相关文献

参考文献27

  • 1Sarkissian T,Beyenne J,Feldman B,et al.The complex nature of the interaction between disease activity and therapy on the lipid profile in patients with pediatric systemic lupus erythematosus[J].Arthritis Rheum,2006,54(4):1283-1290.
  • 2Sarkissian T,Beyene J,Feldman B,et al.Longitudinal exami-nation of lipid profiles in pediatric systemic lupus erythema-tosus[J].Arthritis Rheum,2007,56(2):631-638.
  • 3Borba EF,Bonfa E,Vinagre CG.Chylomicron metabolism is markedly altered in systemic lupus erythematosus[J].Arthritis Rheum,2000,43(5):1033-1040.
  • 4Kodera M,Hayakawa I,Komura K,et al.Anti-lipoprotein lipase antibody in systemic sclerosis:assocition with elevatedserum triglyceride concentrations[J].J Rheumatol,2005,32(4):629-636.
  • 5Rivas L,Zabaleta M,Toro F,et al.Decreased transcription,expression and function of low-density lipoprotein receptor in leukocytes from patients with systemic lupus erythematosus[J].Autoimmunity,2009,42(4):266-268.
  • 6]Kurien BT,Scofield RH.Lipid peroxidation in systemic lupus erythematosus[J].Indian J Exp Biol,2006,44(5):349-356.
  • 7韩爱忠,胡兵,汪俊军.类风湿关节炎和系统性红斑狼疮与动脉粥样硬化的关系[J].医学研究生学报,2009,22(8):866-870. 被引量：5
  • 8Matsuura E,Kobayashi K,Hurley BL,et al.Atherogenic oxidized low-density lipoprotein/beta2-glycoprotein I(oxLDL/beta2GPI)complexes in patients with systemic lupus erythe-matosus and antiphospholipid syndrome[J].Lupus,2006,15(7):478-483.
  • 9Lopez LR,Salazar-Paramo M,Palafox-Sanchez C,et al.Oxidized low-density lipoprotein and beta2-glycoprotein I in patients with systemic lupus erythematosus and increased carotid intima-media thickness:implications in autoimmune-mediated atherosclerosis[J].Lupus,2006,15(2):80-86.
  • 10Navab M,Anantharamaiah GM,Reddy ST,et al.HDL as a biomarker,potential therapeutic target,and therapy[J].Diabetes,2009,58(12):2711-2717.

二级参考文献56

共引文献7

同被引文献55

  • 1Sarkissian T, Beyenne J, Feldman B, et al. The complex nature of the interaction between disease activity and therapy on the lipid profile in patients with pediatric systemic lupus erythemato- sus[J]. Arthritis Rheum, 2006, 54: 1283-1290.
  • 2Sarkissian T, Beyene J, Feldman B, et al. Longitudinal examin- ation of lipid profiles in pediatric systemic lupus erythematosus [J]. Arthritis Rheum, 2007, 56: 631-638.
  • 3Chung CP, Oeser A, Solus J, et al. Inflammatory mechanisms affecting the lipid profiles in patients with systemic lupus erythe- matosus[J]. J Rheumatol, 2007, 34: 1849-1854.
  • 4Siripaitoon B, Osiri M, Vongthavaravat V, et al. The prevalence of dyslipoproteinemia in Thai patients with systemic lupus erythe- matosus[J]. Lupus, 2004, 13: 961-968.
  • 5Borba EF, Bonfa E, Vinaqre CG, et al. Chylomicron metabolism is markedly altered in systemic lupus erythematosus[J]. Arthritis Rheum, 2000, 43: 1033-1040.
  • 6Rivas L, Zabaleta M, Toro F, et al. Decreased transcription, ex- pression and function of low-density lipoprotein receptor in leuko- cytes from patients with systemic lupus erythematosus[J]. Autoim- munity, 2009, 42: 266-268.
  • 7Asanuma Y, Chung CP, Oeser A, et al. Increased concentration of proatherogenic inflammatory cytokines in systemic lupus ery- thematosus: relationship to cardiovascular risk factors [J]. J Rheumatol, 2006, 33: 539-545.
  • 8Sabry A, Elbasyouni SR, Sheashaa HA, et al. Correlation be- tween levels of TNF-alpha and IL-6 and hematological in- volvement in SLE egyptian patients with lupus nephritis [J]. Int Urol Nephrol, 2006, 38: 731-737.
  • 9Shovman O, Gilburd B, Shoenfeld Y. The role of inflammatory eytokines in the pathogenesis of systemic lupus erythematosus- related atherosclerosis: a novel target for treatment [J]. J Rheumatol, 2006, 33: 445-447.
  • 10Chun HY, Chung JW, Kim HA, et al. Cytokine IL-6 and IL-10 as biomarkers in systemic lupus erythematosus [J]. J Clin Im- munol, 2007, 27: 461-466.

引证文献2

二级引证文献19

江苏医药
2012年 第3期

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