心脏死亡器官捐献单中心经验总结

Single-center experience of organ donation after cardiac death

目的总结单中心开展心脏死亡器官捐献（DCD）的病历资料和经验。方法自2010年3月至2011年10月，采用Maastricht分类第Ⅲ类标准作为潜在捐献者的临床选择标准，共发现56例潜在捐献者。56例中，40例未同意捐献，16例同意捐献（其中1例在治疗过程中因全身严重感染放弃了器官获取），最终15例成功捐献，共获取12个肝脏和22个肾脏用于移植。结果12例肝移植受者恢复良好。20例肾移植受者中，2例采用双肾带膀胱袢移植的受者术后切除了移植肾，另外2例术后分别由于移植肾破裂和血栓形成而切除移植肾，其余受者恢复良好。结论公民心脏死亡器官捐献可以扩大供者来源，但需严格掌握潜在捐献者的筛选标准。

Objective To summarize our experience of harvesting and using the organs of donors after cardiac death.Methods Form March 2010 to October 2011,56 potential donors were diagnosed with cardiac death,who conformed to the classification of Maastricht Ⅲ criteria.There were 40 failure cases whose family refused to donate,and one failure case who suffered from serious infection.Finally,the success ratio of donation after cardiac death was 26.8% （15/56）.Twelve livers and 22 kidneys were transplanted into 12 and 20 recipients respectively.Results Twelve cases of liver transplantations had acceptable outcomes. The grafts of 4 cases out of 20 cases of kidney transplantations were removed after transplantation,and other recipients had acceptable outcomes.Conclusion Citizens organ donation after cardiac death can expand the number of suitable organs,but we need to strictly control the criteria for potential donors.