经食管血氧饱和度监测对食管黏膜安全性影响的实验研究

Experimental Study of the Effects of Transesophageal Oxygen Saturation Monitoring on the Safety of Esophageal Mucosa

为研究经食管连续监测动脉血氧饱和度(SteO2)的安全性,将家兔20只,随机分为对照组和高频电刀组,麻醉后将带有2个发光二极管(LED)的氧饱和度检测探头置入食管下段,连接脉搏血氧仪,分别监测2h和6h。监测完毕取2个LED处食管全层组织、探头尖端1cm的近胃端食管全层组织(自身对照)行病理组织学检查。结果显示:两组LED-1、LED-2处食管黏膜切片与自身对照切片的病理检查结果均为黏膜完整,黏膜下层轻度水肿、充血,少量淋巴细胞、单核细胞浸润,病理组织学评分均为2分。结果表明,采用相互匹配的氧饱和度传感器和脉搏血氧仪监测SteO26h是安全的。

The present paper was aimed to study the security of burning during the continuous monitoring of transesophageal arterial oxygen saturation.20 rabbits were randomly divided into two groups：control group and high—frequency electrotome group.All rabbits were implanted with the oxygen saturation detection probes into the lower esophageal after anesthesia.The probes were made up with two light-emitting diode（LED） and then connected with oxygen saturation sensor to monitoring for 2h and 6h,respectively.We then intercepted two luminous points as esophageal specimens and dist the esophageal tissue detection device headend lcm gastric side esophageal specimens（self-contr01） after monitoring,andcarried out pathological examination.The pathological results of the LED-1,LED2 esophageal biopsy and self-control section were mucous integrity,submucosal mildedema,hyperemia,a small number of lymphocytes and mononuclear cell infiltration.All the score of the esophageal tissue histologic was 2.The results showed that montioring the SteO2 not more than 6h was safe with montiored using a matching of oxygen saturation sensor and monitoring esophageal arterial oxygen saturation.