热固耦合式超声骨强度仪的可重复性及相关性研究

Study on the repeatability and correlation of warm-air and solid coupled mode ultrasound bone strength device

目的:评估一款国产热固耦合式超声骨强度仪的可重复性和有效性。方法:选择11名志愿者,用该仪器测得右跟骨的两个超声参数,分别是超声速度(SOS)和宽带超声衰减(BUA),计算每个参数的变异系数均方根百分比(CVRMS%),评估该仪器的短期可重复性;选择18名志愿者,用类似的方法评估该仪器的中期可重复性;选择29名志愿者,用双能X线吸收法(DEXA)测量腰椎骨密度(BMD),并与用该仪器测得的跟骨SOS,BUA值进行相关性分析,评估该仪器的有效性。结果:①超声参数SOS,BUA的短期CVRMS%分别为0.30,4.24;中期CVRMS%分别为0.41,4.20。②SOS与腰椎BMD的相关系数r=0.486(P<0.01),BUA与腰椎BMD的相关系数r=0.629(P<0.01)。结论:与国际主流定量超声(QUS)检测仪器相比,热固耦合式超声骨强度仪具有较高的可重复性和准确性,可用于临床骨质状况评估。

Objective： To evaluate the repeatability and correlation of warm-air and solid coupled mode ultrasound bone strength device made in China. Method： Eleven and eighteen volunteers＇ right calcaneus ultrasound parameters, speed of sound （SOS） and broad- band ultrasound attenuation （BUA）, were detected with the device, percentages of root-mean square of coefficient of variation （CVRMs%） of ultrasound parameters were calculated respectively, and used to assess the short- and middle-term repeatability of the device; 29 volunteers＇ right calcaneus ultrasound parameters （SOS, BUA） were de- tected with the device and bone mineral density （BMD） of lumbar spine were detected with dual energy X-ray absorptiometry （DEXA）. Result： （~）The short-term CVRMs% were 4.24% for BUA, and 0.30% for SOS; the middle-term CVaMs% were 4.20% for BUA, and 0.41% for SOS. （~）The correlations between BMD of lumbar spine were 0.629 （P〈 0.01） for BUA and 0.486 （P 〈 0.01） for SOS. Conclusion： Compared to international top-grade quantitative ultrasound（QUS） testing device, the warm-air and solid coupled mode ultrasound bone strength device has high performance of repeatability and accuracy, so it can be used to assessing bone mass status. Author＇s address Affiliated Provincial Hospital of Anhui Medical University, Hefei, 230000