期刊文献+

信号分子TRIF的研究进展 被引量:18

下载PDF
导出
摘要 Toll样受体(TLRs)作为连接天然免疫和获得性免疫的桥梁,其介导的信号转导通路及其作用一直是人们研究的焦点。由髓样分化因子88(myeloid differentiation primary response protein 88,MyD88)承接的转导途径称为MyD88依赖途径,是几乎所有TLRs信号转导的共同通路(TRL3除外)。
作者 解鸿翔 周红
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2012年第2期217-220,共4页 Chinese Journal of Cellular and Molecular Immunology
基金 国家自然科学基金资助项目(3067090730971301) 江苏大学学生科研立项资助项目(10A107)
  • 相关文献

参考文献1

二级参考文献9

  • 1Lopez-Pedrera C, Buendia P, Cuadrado MJ, et al. Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-κB/Rel proteins via the p38 mitogen-aetivated protein kinase path- way, and of the MEK-1/ERK pathway[J]. Arthritis Rheum, 2006, 54(1) : 301 -311.
  • 2Bohgaki M, Atsumi T, Yamashita Y, et al. The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue fac- tor gene in monocytes stimulated with human monoclonal anti-be- ta2Glycoprotein I antibodies [ J ]. Int Immunol, 2004, 16 (11 ) : 1633 -1641.
  • 3Zhou H, Wolberg AS, Roubey RA. Characterization of monocyte tis- sue factor activity induced by IgG antiphospholipid antibodies and inhi- bition by dilazep[J]. Blood, 2004, 104(8) : 2353 -2358.
  • 4Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transducfion pathway [J]. Cytokine, 2008, 42(2) : 145 -151.
  • 5Lambrianides A, Carroll CJ, Pierangeli SS, et al. Effects of polyclonal IgG derived from patients with different clinical types of the antiphos- pholipid syndrome on monocyte signaling pathways [ J ]. J Immunol, 2010, 184(12) : 6622 -6628.
  • 6Resman N, Vasl J, Oblak A, et al. Essential roles of hydrophobic res- idues in both MD-2 and toll-like receptor 4 in activation by endotoxin [J]. J Biol Chem, 2009, 284(22) : 15052 - 15060.
  • 7Vallabhapurapu S, Karin M. Regulation and function of NF-kappaB transcription factors in the immune system [ J ]. Annu Rev Immunol, 2009, 27:693-733.
  • 8Alard JE, Gaillard F, Daridon C, et al. TLR2 is one of the endotheli-al receptors for beta2-glycoprotein I [ J ]. J Immunol, 2010, 185 ( 3 ) 1550 - 1557.
  • 9严一红,周红,周保成,文海平,许国莹,周芳.TLR4在anti-β2GPⅠ/β2GPⅠ复合物诱导THP-1细胞表达TF中的作用探讨[J].中国免疫学杂志,2010,26(5):396-401. 被引量:10

共引文献2

同被引文献230

引证文献18

二级引证文献99

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部