罗哌卡因在腰硬联合阻滞中的应用研究

Applications study of ropivacaine on epidural anesthesia combined lumbar anesthesia

目的探讨罗哌卡因在腰硬联合阻滞中应用的安全性及效果。方法 360例下腹部及下肢手术患者随机分为硬膜外麻醉组及腰硬联合麻醉组,分别采用罗哌卡因麻醉,比较两组患者术中血流动力学指标、麻醉效果和不良反应。结果两组患者术中收缩压、舒张压、心率无统计学意义,腰硬联合麻醉组患者麻醉起效时间及麻醉持续时间均优于硬膜外麻醉组,腰硬联合麻醉组术后不良反应发生率与硬膜外组比较无统计学意义。结论罗哌卡因硬膜外-腰麻联合阻滞麻醉具有较高的安全性,麻醉效果较好,适宜于下腹部及下肢手术麻醉。

Objective To investigate the effect and safety of ropivacaine on epidural anesthesia combined lumbar anesthesia. Methods All of 360 cases patients with hypogastrium and lower limb operations were randomly divided epidural anesthesia groups （EA） and epidural anesthesia combined lumbar anesthesia （ECLA）, and ropivaeaine were taken in two groups, parameter of hemodynamics, anaesthetic effect and rate of untoward reaction were contrasted, between EA and ECLA. Results The heart rate （HR）, systolic blood pressure （SBP） and diastolic blood pressure （DBP） was identical between two groups before anesthesia, during operations and postoprations, time of taking effeey and time of duration in anesthesia was prevalent in ECLA than in EA, rate of untoward reaction after operations was identical between two groups. Conclusion Ropivaeaine has higher safety and good effect in epidural anesthesia combined lumbar anesthesia, was suitable for applications in hypogastrium and lower limb operations.