摘要
从小叶香茶菜[Isodon parvifolia(Batalin)Hara]的叶中分离到11个单体(Ⅰ—Ⅺ),经鉴定晶Ⅳ为一个新化合物,命名为小叶丁素(parvifolinoic acid),晶Ⅴ—Ⅹ分别鉴定为硬脂酸(Ⅴ),β-谷甾醇(Ⅵ),胡萝卜甙(Ⅶ),齐墩果酸(Ⅷ),乌苏酸(Ⅸ)和2α-羟基乌苏酸(Ⅹ)。初步药理实验表明,晶Ⅳ对人肝癌细胞株 QGY-7703有一定抑制作用。
Eleven compounds were isolated from the leaves of lsodon parvifolia(Batalin)Hara.On the basis of spectral analysis and chemical methods,crystal Ⅳ was identified as a new com- pound,named parvifolinoic acid;Crystals V—X were identified as stearic acid(Ⅴ),β-sito- sterol(Ⅵ),daucosterol(Ⅶ),olenoic acid (Ⅷ),ursoric acid(Ⅸ),2α-hydroxy-ursoric acid (Ⅹ)respectively.Primary pharmacology tests showed that crystal Ⅳ had inhibitory effect against QGY-7703.
关键词
香茶菜
小叶丁素
化学成分
parvifolinoic acid
lsodon parvifolia
lsodon
