我院489例Ⅰ类切口手术围术期抗菌药物使用调查分析

Perioperative Use of Antimicrobial Drugs in 489 Cases of Type Ⅰ Incision Operation

目的调查景德镇市第一人民医院Ⅰ类切口手术围手术期抗菌药物临床使用情况并进行分析,以提高合理用药水平。方法随机抽取景德镇市第一人民医院2011年1-6月出院患者的Ⅰ类切口手术病历489份,根据《抗菌药物临床应用指导原则》对围手术期抗菌药物临床应用进行评价。结果Ⅰ类切口手术围手术期抗菌药物使用率是50.10%,共应用11类19种抗菌药物,其中使用频率较高的抗菌药物是头孢唑啉(29.47%)、头孢替唑(11.26%)、头孢噻肟(9.27%)。抗菌药物使用不合理现象主要有:用药时机不合理(19.22%)、无指证用药(18.40%)、抗菌药物选用不合理(11.25%)、术后用药时间过长(11.25%)、溶媒体积过大(10.02%)、抗菌药物用法用量错误(6.13%)、联合用药不合理(4.09%)。结论应强化临床医师合理应用抗菌药物的意识,加强围手术期抗菌药物临床应用的管理,提高合理用药水平。

Objective To investigate perioperative use of antimicrobial drugs in type Ⅰ incision operation in the first people＇s hospital of Jingdezhen in order to improve rational drug use.Methods Medical records of 489 patients undergoing type Ⅰ incision operation between January and June 2011 in our hospital were randomly selected and perioperative use of antimicrobial drugs was evaluated according to guidelines for clinical application of antibiotics.Results A total of 19 kinds of antimicrobial drugs from 11 categories（50.10%） were used during perioperative period in type Ⅰ incision operation.Drugs used more often were Cefazolin（29.47%）,Ceftezole（11.26%） and Cefotaxime（9.27%）.The inappropriate use of antimicrobial drugs included unreasonable treatment time（19.22%）,drug use with no evidence（18.40%）,irrational choice of antimicrobial drugs（11.25%）,excess postoperative medication（11.25%）,excess solvent volume（10.02%）,wrong amount of antimicrobial drugs（6.13%） and irrational combination medication（4.09%）.Conclusion The consciousness of rational use and clinical management of antimicrobial drugs should be strengthened to improve perioperative application of antibacterials.