甲基强的松龙治疗肾移植术后巨细胞病毒肺炎时体温变化与预后的关系

Study of the relationship between body temperature and prognosis in patients with CMV pneumonia after renal transplantation when treating with methylprednisolone

目的探讨甲基强的松龙治疗肾移植术后巨细胞病毒肺炎时患者体温变化与预后的关系。方法选择符合巨细胞病毒肺炎诊断标准的肾移植术后患者97例，根据使用甲基强的松龙72小时后患者体温变化情况分为体温正常组和发热组，比较两组患者的预后情况。结果发热组患者入住ICU人数及入住时间显著高于体温正常组（P〈0．05），多器官功能障碍综合征和急性呼吸窘迫综合征的发生率显著高于体温正常组（P〈0．05），进展为多器官功能障碍综合征、急性呼吸窘迫综合征的时间显著快于体温正常组（P〈0．05），机械通气的发生率及带机时间、住院时间、死亡率均显著高于体温正常组（P〈0．05）。结论甲基强的松龙治疗肾移植术后巨细胞病毒肺炎患者的体温变化可以反映患者的预后情况。

Objective To study the relationship between body temperature and prognosis in patients with CMV pneumonia after renal transplantation when treating with methylprednisolone. Methods Ninety-seven patients meet to CMV pneumonia diagnostic criteria were divided into body temperature normal group and fever group based on body temperature change after treat with MP 72 beurs,compared study on prognosis was carried out. Results The number and stay time of ICU admission in fever group is significantly higher than normal group （ P 〈 0.05 ）, incidence rate of multiple organs dysfunction syndrome （MODS） and acute respiratory distress syndrome （ARDS） is significantly higher than normal group （ P 〈 0.05 ） ,time to become MODS, ARDS is significantly shorter than normal group（ P 〈 0.05 ） ,incidence rate of mechanical ventilation, length of stay and death rate is significantly higher than normal group （P 〈 0.05）. Conclusion Body temperature change in patients with CMV pneumonia after renal transplantation when treating with MP could reflect prognosis.