雷米芬太尼辅助全麻诱导在腹腔镜短小手术中的应用

Ruimifentanyl assistant induction of general anesthesia in short laparoscopic operation

目的:探讨雷米芬太尼辅助全麻诱导在腹腔镜短小手术中的应用效果。方法:选择腹腔镜短小手术患者2 000例,随机分为雷米芬太尼辅助诱导Ⅰ组和常规诱导Ⅱ组,全麻诱导期每间隔1min测量1次血压,全麻维持期、苏醒期每间隔5min测量1次血压,记录HR、MAP、复苏期的呼吸频率、脉搏血氧饱和度。结果:麻醉诱导面罩加压给氧期、气管插管后手术前期Ⅱ组的心率、血压明显低于Ⅰ组(P<0.01);Ⅱ组使用麻黄碱、阿托品多于Ⅰ组。麻醉维持期、复苏期两组的心率、血压差异没有统计学意义(P>0.05)。苏醒期Ⅱ组呼吸频率、脉搏血氧饱和度明显低于Ⅰ组(P<0.05),Ⅰ组苏醒时间明显早于Ⅱ组(P<0.05);苏醒后Ⅰ组嗜睡的发生率明显低于Ⅱ组(P<0.01)。结论:雷米芬太尼辅助全麻诱导在腹腔镜短小手术中的应用是可行的。

Objective： To explore the effects of ruimifentanyl to assist general anesthesia in short laparoscopic surgery.Methods： 2,000 cases undergoing short laparoscopic surgery were randomly divided into ruimifentanyl group 1 and conventional group 2.Blood pressure was measured at each interval of 1 min during general anesthesia induction,and interval of 5 min during anesthesia maintenance phase and recovering period,along with mean arterial pressure（MAP）,heart rate（HR）,the respiratory rate of recovery period,and oxygen saturation.Result： During the period of anesthesia induction and after tracheal intubation,the heart rate and blood pressure in group 2 were significantly lower than group 1（P0.01）,and the amounts of ephedrine and atropine in group 2 were more than group 1（P0.05）.The difference of heart rate and blood pressure were not significant in the 2 groups during anesthesia maintenance phase and recovery period（P0.05）.The respiratory rate and oxygen saturation in recovery period,the group 2 was significantly lower than group 1（P0.05）.The recovery time in group 2 was longer than group 1（P0.05）,and the rate of drowsiness higher than group 1（P0.01）.Conclusion： General anesthesia assisted by ruimifentanyl is feasible in short laparoscopic surgery.