儿童毛细血管渗漏综合征临床诊治进展

Diagnosis and treatment of capillary leak syndrome in children

毛细血管渗漏综合征是小儿时期较常见的急危重症之一，多由于感染、创伤、休克、窒息、体外循环、缺血再灌注等因素引起，临床表现为严重的水肿、低蛋白血症、低血容量，甚至导致低血容量性休克，进而引起多脏器功能障碍，了解疾病的发病机制、诊断及临床经过，对于合理用药、更好的治疗有重要的指导意义。

Capillary leak syndrome（CLS） is a common and life-threatening disorder in children. The common pathogenies are sepsis, severe trauma, shock, asphyxia, extracorporeal circulation, ischemical reperfusion injury and so on. It is characterized by shock resulting from leakage of plasma, which is refected by accompanying hemoconcentration, hypoalbuminemia and edema, sometimes followed by multiple organ dysfunction syndrome. Clinicians should consider the diagnosis in patients with unexplained edema and hypotension. To know the pathophysiology and clinical course will be benefit to proper medicine choosen.