多西紫杉醇联合化疗法治疗非小细胞肺癌的研究进展

Progress of Docetaxel Combining with Chemotherapy in Treatment of Non-small Cell Lung Cancer

目的介绍多西紫杉醇联合化疗法治疗非小细胞肺癌的研究进展。方法通过查阅国内外的文献资料,讨论多西紫杉醇联合铂类制剂和非铂类第3代药物的临床疗效和不良反应。结果多西紫杉醇联合化疗法治疗非小细胞肺癌疗效确切、不良反应轻微。结论联合化疗方案有望解决单药方案有效率略低的问题,并为非小细胞肺癌的治疗提供临床指导。

OBJECTIVE To introduce the progress of the combined treatment of docetaxel and chemotherapy for non-small cell lung cancer. METHODS By investigating the national and international literatures, the clinical effects and adverse reactions of docetaxel combining with platinum agents and non-platinum drugs were discussed. RESULTS The efficacy was definite and adverse effects were light in treatment of non-small cell lung cancer by docetaxel combining with chemotherapy. CONCLUSION The combined therapy is expected to solve the single-agent problem of low effects and provide the clinical guidance.