银杏叶提取物注射液治疗突发性耳聋量效关系探讨

目的 研究银杏叶提取物注射液剂量与治疗突发性耳聋疗效的相关性.方法 将72例（73耳）突发性耳聋患者随机分为A、B两组,A组42耳,B组31耳,A组42耳治疗方案为：0.9%氯化钠注射液250ml＋银杏叶提取物注射液（金纳多注射液）70mg（4支）静脉滴注,1次/d,共14d,地塞米松10mg莫菲管滴入,1次/d,共3d;B组31患耳治疗方案为：0.9%氯化钠注射液250ml＋银杏叶提取物注射液（金纳多注射液）140mg（8支）静脉滴注,1次/d,共14d,地塞米松10mg莫菲管滴入,1次/d,共3d.结果 A组总有效率66.66%,B组总有效率90.32%,两组之间差异有统计学意义（χ2=4.34,P〈0.05）;结论 银杏叶提取物注射液治疗突发性耳聋效果好且有明显的量效关系.

Objective To explore The relationship of the doseage and effect of ginaton in treating sudden deafness. Methods seventy two patients with sudden deafness were divided into group A and group B at random; 41 patients of group A were treated with 70mg ginaton through IV drips, 31 patients of group B were treated with 140 mg ginaton through IV drips, once a day, the time of treatment is 14days. Results The effective rate of group A was 66. 67%, and the effective rate of group B was 90. 23%, the treating effect was significantly different in the group A and B （ χ2 = 4. 34, P 〈 0. 05 ）. Conclusions It is effective for ginaton to treat sudden deafness, and it has a significant relationship between the doseage and effect in treating sudden deafness with ginaton.