摘要
目的探讨急性脑梗死患者入院时的血清RBP4水平与其早期预后之间的关系。方法选取2008年7月—2010年6月在我科住院的急性脑梗死患者268例,按入院时的血清RBP4水平,分为RBP4升高组118例,RBP4正常组150例,分别测定两组患者入院当时以及出院(或住院2周)时NIHSS评分,并统计两组患者发生进展性卒中和死亡的例数。以两次NIHSS评分差值>4分为预后良好,NIHSS评分差值<4分为预后不良。比较两组患者NIHSS评分的变化,以及发生进展性卒中和死亡的例数。结果 (1)RBP4正常组,早期预后良好的比例明显高于RBP4升高组,差异有统计学意义(P<0.01)。(2)RBP4升高组,发生进展性卒中的例数高于RBP4正常组,差异有统计学意义(P<0.05)。(3)两组患者在早期死亡率上差异无统计学意义(P>0.05)。结论血清RBP4可以作为评判急性脑梗死早期预后的一种生化指标。
Objective To explore the patients with acute cerebral infarction RBP4 level of serum on the relationship between its early prognosis. Methods The July 2008 to June 2010 my branch in acute cerebral infarction patients in hospital, according to admission 268 cases RBP4 level of serum, divided into 118 cases of RBP4 rise, RBP4 group, the normal group 150 patients with two groups were measured at hospital admission （or hospitalization and NIHSS scores when 2 weeks）, and statisti- cal two groups were happen progress sex and death on the number of stroke. With twice NIHSS scores 〉4 poor cost NIHSS scores into prognosis was good, difference value was divided into 4 poor prognosis. Compared two groups of patients NIHSS scores chan- ges, and happen progress sex stroke and death of number. Results （ 1 ） The normal group, early RBP4 significantly higher than the proportion of good prognosis RBP4 rise group, a statisti cally significant difference （P 〈0. 01 ）. （2） RBP4 rise group, the number ofstroke happened progress sex than RBP4, a statistically significant difference （P 〈 0. 05）. （3） Two groups of pa- tients in the early mortality difference was no statistically significant （P 〉 0. 05）. Conclusion Serum RBP4 can serve as judge the prognosis of patients with acute cerebral infarction early a biochemical indicators.
出处
《实用心脑肺血管病杂志》
2012年第3期405-406,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
武汉市卫生局基金资助项目(WX11D15)
