新型手性四氮镍(Ⅱ)配合物的合成、表征及催化苯乙酮不对称氢转移研究被引量：1

Synthesis,Characterization of Ni(Ⅱ) Complexes with Chiral Tetraaza Ligands and Their Application for Asymmetric Transfer Hydrogenation of Acetophenone

下载PDF

导出

摘要合成了两个手性四氮配体,(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]乙二胺(A)和(S,S,S,S)-N,N′-二[2-(对甲苯磺酰胺基)-1,2-二苯基乙基]丙二胺(B),及其手性镍(Ⅱ)配合物1和2,采用元素分析、1 H NMR、MS和IR对它们进行了表征.研究了手性配合物催化苯乙酮的不对称氢转移反应,考察了碱量和反应时间对催化活性的影响. The experiment synthesized two chiral tetraaza ligands, （S, S, S, S）-N, N^1-bis（2-p-toluenesulfonylamino-1, 2-diphenylethyl） ethylenediamine （A） and （S, S, S, S）-N, N^1-bis（2-p-toluenesulfonylamino-1, 2-diphenylethyl） trimethy- lenediamine （B）, and characterized their Ni（Ⅱ） complexes by elemental analysis, ^1H-NMR, MS and IR. The paper researched on the asymmetric hydrogen transfer reaction of acetophenone, and investigated the effects of the alkali charge and reaction time on ATH.

作者张添谭华杰洪益玲沈良

机构地区杭州师范大学材料化学与化工学院

出处《杭州师范大学学报（自然科学版）》 CAS 2012年第1期7-10,16,共5页 Journal of Hangzhou Normal University(Natural Science Edition)

基金浙江省自然科学基金项目(Y4090056)

关键词手性四氮配体镍配合物苯乙酮不对称氢转移 chiral tetraaza ligands nickel complex acetophenone asymmetric transfer hydrogenation

分类号 O69 [理学—化学]

引文网络
相关文献

参考文献3

1杨朝芬,付海燕,熊伟,薛芳,林棋,陈华,李贤均.手性二胺修饰的镍配合物催化苯乙酮及其衍生物的不对称加氢反应[J].化学研究与应用,2007,19(4):361-365. 被引量：6
2杨瑞丽.水合醋酸镍和硫酸镍铵的热分析研究[J].咸阳师范学院学报,1998,14(6):24-26. 被引量：3
3洪益玲,沈良,谭华杰.手性磺酰二胺配合物催化芳香酮的不对称氢转移研究进展[J].杭州师范大学学报（自然科学版）,2010,9(1):57-64. 被引量：1

二级参考文献54

1熊伟,杨朝芬,袁茂林,陈华,李贤均.水/有机两相体系中钌膦配合物催化苯乙酮及其衍生物的不对称加氢反应[J].催化学报,2005,26(12):1093-1098. 被引量：8
2Chen Yingchun, Wu Tongfei, Jiang Yaozhong, et al. Synthesis of dendritic catalysts and application in asymmetric transfer hydrogenation[J]. J Org Chem, 2005,70(3) : 1006-1010.
3Chen Yingehun, Wu Tongfei, Deng Jingen, et al. Multiple dendritic catalysts for asymmetric transfer hydrogenation[J]. J Org Chem, 2002,67(15) : 5301-5306.
4Geldbaeh T J, Dyson P J. A versatile ruthenium precursor for biphasic catalysis and its application in ionic liquid biphasic transfer hydrogenation: conventional vs task-specific eatalysts[J]. J Am Chem Soc,2004,126(26):8114-8115.
5Kawasaki I, Tsunoda K, Ohta S, et al. A recyclable catalyst for asymmetric transfer hydrogenation with a formic aeid-triethylamine mixture in ionic liquid[J]. Chem Commun,2005,16:2134-2136.
6Okano K, Murata K, Ikariya T. Stereoselective synthesis of optically active pyridyl alcohols via asymmetric transfer hydrogenation of pyridyl ketones[J]. Tetrahedron Letter,2000,41(48):9277-9280.
7Hansen K B, Chilenski J R, Mathre D J, et al. Scalable, efficient process for the synthesis of(R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex[J]. Tetrahedron: Asymmetry, 2003,14 (22) :3581-3587.
8Hashiguchi S, Ikariya T, Noyori R, et al. Asymmetric transfer hydrogenation of aromatic ketones catalyzed bychiral ruthenium(Ⅱ) complexes[J]. J Am Chem Soc, 1995,117(28) :7562-7563.
9Blaser H U,Schmidt E.工业规模的不对称催化[M].上海:华东理工大学出版社,2006:189-203.
10Murata K, Ikariya T, Noyori R. New chiral rhodium and iridium complexes with chiral diamine ligands for asymmetric transfer hydrogenation of aromatic ketones[J]. J Org Chem,1999,64(7):2186-2187.