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α-羟基酸类物质的酶法还原 被引量：1

Enzymatic Reduction of α-Hydroxy Acids
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摘要 手性纯α-羟基酸类化合物是合成手性药物和农药的重要中间体.多种酶催化过程都能用于α-羟基酸类物质的合成.酮还原酶是最有应用价值的工具酶之一.文章对酮还原酶还原合成α-羟基酸类物质进行综述. Chiral a-hydroxy acids are important intermediate for the synthesis of drugs and pesticides. Various enzymatic processes can be used into the synthesis of α-hydroxy acids. Ketoreductase is the most useful＇ enzymes. This paper summarized the synthesis of a-hydroxy acids by ketoreductase.
作者 吕丹青 张朝晖 陈振明
机构地区 杭州师范大学生物催化研究室 浙江工业大学生物与环境工程学院
出处 《杭州师范大学学报（自然科学版）》 CAS 2012年第1期33-37,共5页 Journal of Hangzhou Normal University(Natural Science Edition)
关键词 Α-羟基酸 酮还原酶 手性合成 α-hydroxy acids ketoreductase chiral synthesis
分类号 Q814.9 [生物学—生物工程]
  • 相关文献

参考文献28

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共引文献2

同被引文献14

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杭州师范大学学报（自然科学版）
2012年 第1期

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