原发性甲状腺功能减退症并心包积液临床分析

Clinical analysis of the primary hypothyroidism patients with pericardial effusion

目的探讨原发性甲状腺功能减退症发生心包积液的临床特点。方法对38例原发性甲状腺功能减退症患者进行回顾性分析,根据超声心动图检查结果分为合并心包积液组19例与无心包积液组19例。分别对两组患者的临床特征:甲状腺功能、血液系统、肝功能、血脂水平、心脏彩色多普勒检查等进行两样本t检验。结果合并心包积液组患者的甲状腺激素(TH)、血红蛋白(HB)、射血分数(EF)、白蛋白(ALB)水平均显著低于无心包积液组(P<0.05)。结论原发性甲状腺功能减退症发生心包积液易合并多系统功能障碍,在甲状腺激素水平极低,及合并贫血、低蛋白血症的时候应行心脏彩色多普勒检查排除心包积液可能。

Objective Our aim is to find clinical features of primary hypothyroidism with pericardial effusion.Methods Thirty-eight patients with primary hypothyroidism were retrospectively analyzed.They were divided into 19 patients with and 19 patients without pericardial effusion according to the results of echocardiography.Two-samples t test was used to analyze the clinical features including thyroid hormones,blood tests,liver function,lipid levels and heart color Doppler ultrasound in two groups of patients.Results The levels of thyroid hormone（TH）,hemoglobin（HB）,ejection fraction（EF）,and albumin（ALB） in primary hypothyroidism patients with pericardial effusion were significantly lower than those in primary hypothyroidism patients without pericardial effusion（P〈0.05）.Conclusion Multi-system dysfunction may occur in the primary hypothyroidism patients with pericardial effusion.When patients show low thyroid hormone levels,anemia and hypoproteinemia,cardiac color Doppler examination should be done to rule out possible pericardial effusion. 更多