期刊文献+

氨柔比星对治疗一线含铂化疗后复发患者的意义:一项多中心Ⅱ期临床研究的结果 被引量:1

Phase Ⅱ Study of Amrubicin as Second-Line Therapy in Patients with Platinum-Refractory Small-Cell Lung Cancer
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摘要 3背景 小细胞肺癌占肺癌的15%,在确诊的时候已有60%~70%处于广泛期。尽管小细胞肺癌初治患者对化疗药物较敏感,但很快产生耐药性并复发,且复发患者的预后很差。
作者 王洁 陈志勇
出处 《循证医学》 CSCD 2012年第1期38-40,共3页 The Journal of Evidence-Based Medicine
关键词 小细胞肺癌 复发 氨柔比星 small-cell lung cancer refractory Amrubicin
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参考文献4

  • 1Jotte R, Conkling P, Reynolds C, et al. Randomized phase I1 trial of single-agent Amrubicin or Topotecan as second-line treatment in patients with small-cell lung cancer sensitive to first-line platinum-based chemotherapy[J]. J Clin Oncol, 2011, 29 ( 3 ) : 287-293.
  • 2Schmittel A. Second-line therapy for small-cell lung cancer [ J ]. Expert Rev Anticancer Ther, 2011,11 (4) : 631-637.
  • 3Nogami N, Hotta K, Kuyama S, et al. A phase 11 study of Amrubicin and Topotecan combination therapy in patients with relapsed or extensive-disease small-cell lung cancer: Okayama lung cancer study group trial 0401[J]. Lung Cancer, 2011,74 (1) :80-84.
  • 4Zatlouka| P, Cardenal F, Szczesna A, et al. A multicenter international randomized phase m study comparing Cisplatin in combination with Irinotecan or Etoposide in previously untreated small-cell lung cancer patients with extensive disease [J]. Ann Oncol, 2010, 21(9): 1810-1816.

同被引文献18

  • 1曹子昂.2014第一版NCCN小细胞肺癌治疗指南解读[J].中国医学前沿杂志(电子版),2013,5(12):79-81. 被引量:26
  • 2陈东福,吕纪马,周宗枚,王绿化,张宏兴,冯勤富,梁军,肖泽芬,张世平,张香茹,殷蔚伯.放射治疗在广泛期小细胞肺癌治疗中的影响[J].医学研究杂志,2006,35(4):15-17. 被引量:16
  • 3Ding Q, Zhan J.Amrubicin:potential in combination with cisplatin or carboplatin to treat small-cell lung cancer[J]. Drug Des Devel Ther, 2013(7):681-689.
  • 4Sgambato A, Casaluce F, Maione P, et al. Medical treatment of small cell lung cancer: state of the art and new development[J]. Expert Opin Pharmacother, 2013, 14(15):2019-2031.
  • 5Kitagawa C, Saka H, Kajikawa S, et al. Phase I and pharmacologic study of weekly amrubicin in patients with refractory or relapsed lung cancer: Central Japan Lung Study Group(CJLSG) 0601 trial[J]. Cancer Chemother Pharmacol, 2012, 69(5): 1379- 1385.
  • 6Kawahara M, Kubo A, Komuta K, et al. A phase I study of amruhicin and fixed dose of irinotecan (CPT-11) in relapsed small cell lung cancer:Japan multinational trial organization LC0303[J]. J Thorac Oncol, 2012, 7(12):1845-1849.
  • 7Sugiura T, Ariyoshi Y, Negoro S, et al. Phase I / II study of amrubicin, a novel 9-aminoanthracycline, in patients with advanced non-small-cell lung cancer[J]. Invest New Drugs, 2005, 23(4):331-337.
  • 8Mitsuoka S, Kudoh S, Kimura T, et al. Clinical outcome of amrubicin therapy according to the prior chemotherapy sensitivities of extensive small cell lung cancer[J]. Osaka City Med J, 2011, 57(2):59-66.
  • 9Cui JJ, Tran-Dub6 M, Shen H, et al. Structure based drug design of crizotinib(PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor(c-MET) kinase and anaplastic lymphoma kinase(ALK)[J]. J Med Chem, 2011, 54(18):6342-6363.
  • 10Igawa S, Yamamoto N, Ueda S, et al. Evaluation of the recommended dose and efficacy of amrubicin as second-and third-line chemotherapy for small cell lung cancer[J]. J Thorac Oncol, 2007, 2(8):741-744.

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