摘要
目的探讨因胃癌术后胃瘫引发韦尼克脑病的病因、诊断和治疗方法。方法回顾性分析2000年8月至2010年12月收治的6例胃癌术后胃瘫并发韦尼克脑病患者的临床资料。结果胃癌患者816例的治疗过程中发生胃瘫32例(3.9%),在32例胃瘫中并发韦尼克脑病6例(18.8%),多发生在胃癌术后胃瘫后第1~2周。4例(66.7%)经及时诊断后补充维生素B1症状消失,2例(33.3%)因延误治疗而留有后遗症。结论胃癌术后胃瘫患者及时补充维生素B1是预防及治疗韦尼克脑病发生的关键。
Objective To investigate the cause, pathogenesis, diagnosis and treatment ofWernicke encephalopathy (WE) associated with gastroplegia after operation for gastric cancer. Methods Clinical data of 6 patients who had WE associated with gastroplegia after gastrectomy were analyzed retrospectively. Results In 816 patients with gastric cancer, 32 (3.9%) patients developed gastroplegia after operation. In the 32 patients with gastroplegia, 6 patients ( 18.8% ) developed WE within 2 weeks. Four patients with WE (66.7%) were treated successfully with vitamin B1 in time; however, 2 patients (33.3%) developed delayed sequelae due to misdiagnosis. Conclusions Supplement of vitamin B1 is proposed to prevent and treat WE associated with gastroplegia after gastrectomy.
出处
《中华普外科手术学杂志(电子版)》
2012年第1期60-62,共3页
Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
关键词
韦尼克脑病
硫胺素
胃肿瘤
手术后并发症
Wernicke encephalopathy
Thiamine
Stomach neoplasms
Postoperative complications