重度外阴阴道假丝酵母菌病阴道微生态分析

The microecological evaluation of vaginal microflora in the women of serious vulvovaginal candidiasis.

目的了解重度外阴阴道假丝酵母菌病(serious vulvovaginal candidiasis,SVVC)患者的阴道微生态情况。方法对2008年8月至2009年3月北京大学第一医院SVVC患者共150例,进行阴道分泌物微生态检测。结果 (1)优势菌仍以乳酸杆菌为主,占74%,阴道菌群密集度多在Ⅱ～Ⅲ级,占80.67%;阴道菌群多样性多在Ⅱ～Ⅲ级,占76%。(2)清洁度为Ⅰ度的患者60例,占40%,Ⅱ度的患者53例,占35.33%,Ⅲ度的患者37例,占24.67%。(3)pH<4.5占68%。结论重度外阴阴道假丝酵母菌病存在着一定程度的阴道微生态紊乱,但是优势菌仍以乳酸杆菌为主,阴道菌群密集度和多样性大部分仍在正常范围。

Objective To investigate the microecological evaluation of vaginal microflora in the women of SVVC. Methods 150 women of SVVC were studied by collecting vaginal secretion, and the vagina pH and microecological evaluation based on Gram stained smear were tested. Results （ 1 ） 74 % of advantage microflora were lactobacillus, and 80. 67 % of the degree of microflora intensive of cases were Ⅱ-Ⅲ, 76% of the degree of microflora diversity were Ⅱ-Ⅲ. （2） There were 60 cases of cleanness Ⅰ （40%） , 53 cases of cleanness Ⅱ （35.33%） , 37 cases of cleanness Ⅲ（24. 67% ）. （3） About 68% of them pH was 〈 4. 5. Conclusion SVVC exist a certain degree disorder of vaginal microecosystem, the advantage microflora still are lactobacillus, the degree of microflora intensive and the degree of microflora diversity of the mainly patients are in normal range.