应用现代发酵技术生产植物源珍稀药物的产业化前景——以天然抗癌药物紫杉醇为例

Industrial Perspective of Modern Fermentation Technology Applied in Taxol Production

紫杉醇(Paclitaxel,商品名Taxo1)是当今世界公认的广谱、疗效确切的二萜类抗癌药物,广泛用于卵巢癌、乳腺癌等的治疗。本文对紫杉醇的药用价值及其生产技术概况进行了综述,尤其就利用现代发酵技术解决紫杉醇药源稀缺问题的前景进行了详细探讨。

Taxol is a highly functionalized,diterpene anticancer drug,which was widely used in treating breast and ovarian cancers.This paper summarized the research advances of taxol＇s application value and production technology of,especially discussed the potential perspective of the modern frementation technology as a new approach to resolve the lack of taxol.