天津市宁河县肝癌及乙型病毒性肝炎发病分析

Morbidity Analysis of Liver Cancer and Viral Hepatitis B during 1988 to 2010 at Ninghe County in Tianjin

目的对宁河县1988-2010年肝癌、乙型病毒性肝炎发病进行统计分析,为制定肝癌、乙型病毒性肝炎防控策略提供依据。方法收集天津市宁河县1988-2010年乙型病毒性肝炎和肝癌发病的报告资料,计算发病粗率和标化发病率。结果 1988-2010年宁河县肝癌标化发病率为22.43/10万,超过天津市肝癌发病率10.22/10万一倍多。1988-2006年,肝癌年标化发病率在7.45/10万～29.65/10万之间,呈逐年上升趋势,高峰期在1990-2006年,经趋势检验,χ2=4.8662,P<0.001。2007年后肝癌发病率逐年下降。乙型病毒性肝炎发病率在1990年为2/10万,2006年达高峰(43/10万)。2008年1月-2010年9月全民开展乙肝疫苗接种后,2010年比2007年乙型病毒性肝炎发病率下降了36.2%,其中,农民乙型病毒性肝炎病例减少了32.8%,学生病例减少了22.2%,机关事业单位病例减少了76.9%,0～14岁儿童发病率低于1/10万,学生和机关单位人员发病率均低于4/10万。结论宁河县肝癌发病率远高于天津市肝癌发病率;肝癌和乙型病毒性肝炎发病率自2007年均开始下降。

Objective To analyze the morbidity of liver cancer and viral hepatitis B from 1988 to 2010 at Ninghe County in Tianjin. Methods The report date of the incidence of liver cancer and hepatitis B from 1988 to 2010 at County Ninghe were collected. The crude and standardized morbidity rate （SMR） was calculated. Results The SMR of liver cancer from 1988 to 2010 at County Ninghe was 22.43/100 000, which was nearly twice as much as the average level of liver cancer incidence （ 10.22/100 000） in Tianjin. The peak SMR was located at year 1990 to 2006, and then it declined. The incidence of hepatitis B was 2/100 000 in 1990 and it reached to the peak value of 43/100 000 in 2006. After vaccination against hepatitis B for whole residents at Ninghe county from January 2008 to September 2010, the incidence of hepatitis B in 2010 decreased by 36.2% than that in 2007.The rate in peasants dropped by 32.8%, the rate in students dropped by 22.2% and the rate in government staff dropped by 76.9%. The incidence of hepatitis B in government staff and students were lower than 1/100 000 and 4/100 000, respectively. Conclusion The incidence of liver cancer at Ninghe County was higher than the average level of Tianjin. The incidences of liver cancer and hepatitis B declined from 2007.