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钯/铜协同催化合成3,4-二氢香豆素衍生物

Pd/Cu-Catalyzed Synthesis of 3,4-Dihydrocoumarin Derivatives
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摘要 以Baylis-Hillman加成物为起始原料,经过氢溴酸溴代,得到溴代物2,再与2-萘酚反应得到醚化物3;首次报道利用Pd(OAc)2/Cu(OTf)2复合催化剂催化醚化物3的环化反应,得到4个3,4-二氢香豆素类衍生物(4a^4d),并通过1H NMR和MS进行表征。 Aryl allyl ethers（3） were synthesized by bromation and esterization of Baylis-Hillman adducts（1）.Four 3,4-dihydrocoumarin derivatives were obtained by cyclization of aryl allyl ethers（3） in the presence of Pd（OAc）2/Cu（OTf）2.The structures were confirmed by 1H-NMR and MS.
作者 王晗深 邵江斌 邓云 刘运奎 许响生
机构地区 浙江工业大学化学工程与材料学院
出处 《浙江化工》 CAS 2012年第1期22-24,共3页 Zhejiang Chemical Industry
关键词 Baylis-Hillman加成物 香豆素 PD(OAC)2 Cu(OTf)2 Baylis-Hillman adducts Coumarin Pd（OAc）2 Cu（OTf）2
分类号 TQ25 [化学工程—有机化工]
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参考文献11

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浙江化工
2012年 第1期

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