摘要
目的应用实时三维超声心动图(RT-3DE)评价急性和陈旧性前壁心肌梗死患者左室整体节段舒缩功能及室壁运动同步性,并探讨左室整体及局部舒缩功能对左心室室壁运动同步性的影响。方法急性前壁心肌梗死组20例,陈旧性前壁心肌梗死组25例,正常对照组22例,均行常规二维及RT-3DE检查,通过Qlab 6.0定量分析软件分析整体及节段容积-时间曲线,获取左室整体和节段舒张末期容积(EDV,rEDV)、整体和节段收缩末期容积(ESV,rESV)、左室整体和节段射血分数及其平均值(LVEF,rEF,rEF')、节段-整体射血分数及其平均值(rgEF,rgEF')、左室最大射血速率和充盈速率(PER,PFR);左室16节段达到最小收缩容积的时间的标准差值校正值(Tmsv16-SD%)。结果两组前壁心梗患者左室整体EDV、ESV、Tmsv16-SD%均较正常对照组增大,LVEF、PER/EDV、PFR/EDV均较正常对照组减小(P<0.05),梗死节段及邻近梗死区域的大部分rEDV、rESV均较正常对照组增大,rEF、rgEF均较正常对照组减小(P<0.05);两组前壁心梗患者的大部分参数差异无显著性。LVEF、PER/EDV、PFR/EDV、rEF'、rgEF'与SDI均呈负相关;rEF'、rgEF'与LVEF呈正相关。结论 RT-3DE能够准确评价急性和陈旧性心肌梗死患者左室整体节段舒缩功能及室壁运动同步性,左室整体节段舒缩功能减退会影响室壁运动同步性。
Objective To evaluate left ventricular global and regional systolic diastolic function and wall motion synchronism,and to explore the impact of left ventricular global and regional systolic diastolic function and wall motion synchronism in patients with acute and old anterior myocardial infarction by real-time three-dimensional echocardiography（RT-3DE）.Methods Twenty patients with acute anterior myocardial infarction,twenty-five patients with old anterior myocardial infarction and twenty-two normal subjects were enrolled in this study with underwent two-dimensional echocardiography and RT-3DE.Then global and regional volume-time curve was analyzed with Qlab 6.0 software.Acquired the left ventricular global and regional end diastolic volume（EDV）,global and regional end systolic volume（ESV）,global,regional and the mean value ejection fraction（EF）,regional stroke volume toglobal diastolic volume and the mean value,left ventricular peak ejection rate（PER） and peak flow rate（PFR）,the time of minimal systolic volume of 16-segmental＇ standard deviation（Tmaso 16-SD%） correction value.Results Compared with control group,left ventricular global EDV,ESV and Tmsv16-SD% in the patients with anterior myocardial infarction were larger,while EF,PER/EDV,PFR/EDV were lower（P0.05）.The most rEDV,rESV were larger,while rEF and rgEF were lower in the zones with infarction and adjacent segments（P0.05）.There were no significant differences between the two anterior myocardial infarction groups with the most parameters.There was negative correlation among LVEF,PER/EDV,PFR/EDV,rEF′,rgEF′ and SDI,while there was positive correlation among rEF′,rgEF′and LVEF.Conclusion RT-3DE can be used to assess accurately left ventricular global and regional function and wall motion synchronism.The left ventricular global and regional systolic and diastolic dysfunction has effect negatively on wall motion synchronism in patients with acute and old anterior myocardial infarction.
出处
《安徽医科大学学报》
CAS
北大核心
2012年第2期167-171,共5页
Acta Universitatis Medicinalis Anhui
