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FCRL3基因rs7522061位点多态性与类风湿性关节炎遗传易感性的关系 被引量：1

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摘要 目的探讨类风湿性关节炎(RA)遗传易感性与FCRL3的单核苷酸多态性的关系。方法采用病例对照法,分别收集RA患者和正常对照各184例,通过连接酶检测反应方法检测FCRL3 rs7522061位点的基因型,分析基因型及等位基因频率在两组中的分布。结果 FCRL3 rs7522061位点的等位基因频率和基因型频率在病例组和对照组中的分布差异无统计学意义(χ2=0.815,P=0.367;χ2=0.865,P=0.649)。结论安徽省汉族RA患者遗传易感性与FCRL3rs7522061位点无关。
作者 曾臻 潘发明 段振华 王笙 李桂兴 徐胜前 徐健华 张天琛 张立
机构地区 安徽医科大学公共卫生学院流行病与卫生统计学系 安徽医科大学第一附属医院风湿免疫科 安徽医学高等专科学校省遗传医学中心
出处 《安徽医科大学学报》 CAS 北大核心 2012年第2期206-208,共3页 Acta Universitatis Medicinalis Anhui
基金 国家自然科学基金(编号:30771849 30972530) 安徽省自然科学基金(编号:090413133)
关键词 FCRL3基因 多态性 类风湿性关节炎 易感性
分类号 R593.22 [医药卫生—内科学] R181.33 [医药卫生—流行病学]
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安徽医科大学学报
2012年 第2期

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