地奈德乳膏对青少年特应性皮炎疗效的研究

A randomized controlled trial about efficacy of desonide cream in Adolescents' atopic dermatitis

目的观察地奈德乳膏治疗青少年特应性皮炎的疗效和不良反应。方法将本院80例青少年特应性皮炎患者随机分为两组,试验组40例外用地奈德乳膏,对照组40例外用丁酸氢化可的松乳膏治疗,疗程为3周。结果试验组有效率为90.0%,对照组有效率为72.5%,两组治疗有效率差异有统计学意义(P<0.05);试验组无不良反应。结论地奈德乳膏治疗青少年特应性皮炎的效果好,不良反应发生率低。

Objective To observe the efficacy andadverse reaction of desonide cream in the treatment on atopic dermatitis in Adolescents.Methods The patients were randomly assigned to either test group（n=40） treated with desonide cream or control group（n=40） with hydrocortisone butyrate.The courses of the two groups were all 3 weeks.Results The effective rate of the test group treated with desonide cream was 90.0%,the effective rate of the control group treated with hydrocortisone butyrate was 72.5%,the effective rate＇s differences between the two groups were statically significant.Conclusion The efficacy of atopic dermatitis in Adolescents is good,the incidence of adverse reactions is low.