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恶性肿瘤患者化疗前后免疫学指标的变化及临床应用探讨 被引量：5

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摘要 目的观察恶性肿瘤患者化疗前后外周血免疫学指标的变化,并探讨其临床应用。方法应用流式细胞仪检测100例恶性肿瘤患者化疗前后外周血T淋巴细胞亚群(CD3+、CD4+、CD8+),B淋巴细胞(CD19+)及NK细胞(CD3-/CD16+56+)的表达率。结果所有患者化疗后CD3+、CD4+、CD4+/CD8+表达高于化疗前,NK细胞明显降低,差异有统计学意义(P<0.05);B淋巴细胞(CD19+)化疗前后的变化差异无统计学统计学意义(P>0.05)。结论有效的化疗能够改善恶性肿瘤患者的T淋巴细胞免疫功能。
作者 黄晶
机构地区 河南省驻马店市中心医院
出处 《中国医学创新》 CAS 2012年第4期22-23,共2页 Medical Innovation of China
关键词 恶性肿瘤 化疗 T淋巴细胞亚群 B淋巴细胞 NK细胞 流式细胞术
分类号 R730.5 [医药卫生—肿瘤]
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参考文献5

二级参考文献28

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共引文献31

同被引文献61

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中国医学创新
2012年 第4期

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