癌相关成纤维细胞与口腔肿瘤关系的研究进展
被引量:2
摘要
肿瘤的发生发展不仅依赖肿瘤细胞本身的恶性增殖,更依赖于肿瘤间质微环境结构和功能上的支持。癌相关成纤维细胞(CAFs)是肿瘤微环境中最主要的宿主细胞,通过细胞间的直接接触、可溶性因子的分泌和对细胞外基质的修饰等方式对肿瘤的发生发展起着重要的调控作用。本文就CAFs及其与口腔肿瘤发生发展关系的研究进展进行综述。
出处
《临床口腔医学杂志》
2012年第2期121-124,共4页
Journal of Clinical Stomatology
基金
内蒙古医学院附属医院重大科研项目基金资助(NYFYZD2010007)
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