早产儿383例ROP筛查情况分析报告

Analysis report for retinopathy of prematurity screening in 383 cases

目的:分析泉州地区早产儿视网膜病变(retinopathy of prematurity,ROP)发病情况及高危因素。方法:回顾2010-10/2011-09在我院NICU及眼科门诊进行视网膜病变筛查的383例早产儿眼底情况,并进行汇总分析。结果:在筛查的383例早产儿中,发现ROP患儿53例(13.8%),均为双眼发病;其中阈值前Ⅰ型及阈值期病变光凝治疗22例(5.7%);发展为5期病变1例(0.3%);急进型2例(0.5%)。数据显示ROP的发病率及严重程度与出生体质量及胎龄呈负相关;尤其出生体质量与ROP的发生关系密切。结论:低出生胎龄和体质量是ROP发生的根本性高危因素,对于低胎龄、低体质量的高危早产儿应规范进行眼底筛查。

AIM：To analyse the incidence and risk factors of retinopathy of prematurity（ROP） in Quanzhou region.METHODS：The fundus of 383 premature infants were reviewed,who were examined in Ophthalmology clinic and NICU from October 2010 to September 2011,and a meta-analysis was performed.RESULTS：In all the 383 premature infant cases,ROP was found in 53 cases,accounted for 13.8%,all binocular.Pre-threshold typeⅠROP in 22 cases,accounted for 5.7%,which were treated with photocoagulation therapy.The 5 period ROP was in 1 case,accounted for 0.3%.Aggressive posterior ROP was in 2 cases,accounted for 0.5%.Data also showed that the incidence and severity of ROP had a negative corrlation with birth weight and gestational age,especially birth weight.CONCLUSION：Low birth weight and gestational age are the fundamental risk factors of ROP.We should develop standard ROP screening for those high risk premature infants.