急性前葡萄膜炎142例临床分析

Clinical analysis of 142 cases of acute anterior uveitis

目的:探讨应用激素治疗急性前葡萄膜炎的方法、疗效,以减少复发率。方法:对142例急性前葡萄膜炎病例常规给予局部结膜下注射地塞米松2～3mg,1次/d。同时局部点用典必殊及1g/L双氯芬酸钠眼药水。个别病例经局部激素治疗后不能控制病情,则予口服大剂量强的松80～100mg,逐日减量10～20mg,3～5d停药,一般不超过1wk,继续局部激素治疗。结果:全部病例于30d内痊愈,未出现全身并发症,6mo内无1例复发,1a内复发率14.8%(21例)。结论:大多数急性前葡萄膜炎不需全身激素治疗,同时适当延长疗程可能对降低复发率有效。

AIM：To explore the methods and efficacy of hormone therapy of acute anterior uveitis,to reduce the recurrence rate.METHODS：Totally 142 cases of acute anterior uveitis were given conventional topical subconjunctival injection of dexamethasone 2-3mg,1 time/day,at the same time local allusions of TobraDex and 1g/L diclofenac sodium eye drops.Individual cases could not control the disease by topical steroid therapy,then resorted to high-dose oral prednisone 80-100mg,10-20mg daily reduction,withdrawal afer 3-5 days,generally not more than 1 week,and continued topical steroid therapy.RESULTS：All patients healed within 30 days,without any systemic complications,without recurrence within six months,the relapse rate was 14.8%（21 cases） within a year.CONCLUSION：The majority of acute anterior uveitis need not systemic hormone therapy,at the same time prolonged courses of treatment may be effective to reduce the recurrence rate.