贲门失弛缓症的治疗

Treatment of Achalasia

贲门失弛缓症是一种病因尚未明确、累及食管平滑肌和下食管括约肌(LES)的动力障碍性疾病。以吞咽时食管体部蠕动消失、LES松弛障碍为特征。本病的治疗方式包括药物、注射肉毒杆菌毒素、气囊扩张术和肌切开术,旨在降低LES压力,促进食管排空,多数患者可获得较理想的结局。本文就贲门失弛缓症的治疗现状作一综述。

Achalasia is an esophageal motility disorder with unknown etiology,involving the esophageal smooth muscle and lower esophageal sphincter（LES）,characterized by the absence of peristalsis in esophageal body and failure of LES relaxation in response to swallowing.The treatment of achalasia includes pharmacologic agents,botulinum toxin injection,pneumatic dilation and myotomy,so as to reduce the LES pressure and facilitate esophageal emptying,and most patients can achieve excellent results.This article reviewed current status about the treatment of achalasia.