间质性肺疾病合并呼吸衰竭相关因素及机械通气治疗价值

Interstitial Lung Disease with Respiratory Failure Related Factors and the Value of Mechanical Ventilation

目的分析间质性肺疾病(ILD)合并呼吸衰竭的相关因素,并探讨机械通气的治疗价值。方法回顾性分析我院自2006年6月至2011年6月收治的间质性肺疾病合并呼吸衰竭应用机械通气治疗的42例患者的临床资料。结果呼吸衰竭相关因素有ILD急性加重,呼吸道感染,肺栓塞,心力衰竭;急性期7d、14d、30d的生存率依次为97.6%、92.9%、83.3%。有创机械通气病死率88.33%,无创机械通气病死率56.67%,两组组间差异显著,P<0.05。住院总病死率64.28%。结论呼吸道感染、ILD急性加重、肺栓塞及合并心力衰竭是呼吸衰竭相关因素,无创通气治疗效果优于有创通气。

Objective Interstitial lung disease （ILD） with respiratory failure related factors, and to explore the therapeutic value of mechanical ventilation. Methods A retrospective analysis of our hospital from June 2006 to June 2011 were treated with interstitial lung disease with respiratory failure of mechanical ventilation in the treatment of 42 patients with clinical data. Results Respiratory failure, acute exacerbation of ILD-related factors, respiratory infections, pulmonary embolism, heart failure; acute 7d, 14d, 30d of the survival rate of turn 97.6%, 92.9%, 83.3%. lhvasive mechanical ventilation mortality was 88.33%, non-invasive mechanical ventilation mortality was 56.67%, significant differences between the two groups, P〈0.05. The total hospital mortality was 64.28%. Conclusion Respiratory infections, ILD acute exacerbation, pulmonary embolism and respiratory failure complicated by heart failure is related factors, non-invasive ventilation therapy is superior to invasive ventilation.