摘要
胃肠动力紊乱性疾病的观察和研究在儿科仍属初级阶段,小肠平滑肌毒蕈碱样胆碱能受体平衡的变化、L型钙离子通道活力改变及Cajal间质细胞网络和数量的改变在小肠平滑肌功能紊乱发病机制中有着重要的意义。该文重点阐述毒蕈碱样胆碱能受体、L型钙离子通道及Cajal间质细胞三大因素在导致小肠动力紊乱中的作用机制。
The research of pediatric gastrointestinal motility disorders is still in the early stage.It is found that the altered homeostasis of muscarinic receptors,the activity changes of l-type Ca2+ channels,and the network and quantity of interstitial cells of Cajal in intestinal smooth muscle played important roles on pathogenesis of intestinal smooth muscle dysfunction.This review focuses on the effects of muscarinic receptor,L-type Ca2+ channels and interstitial cells of Cajal on intestinal smooth muscle dysfunction.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2012年第2期195-197,共3页
Journal of Clinical Pediatrics
基金
南通大学校级自然科学基金资助项目(No.10Z46)