期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

乳腺(癌)干细胞与Wnt信号通路 被引量：2

下载PDF
导出
摘要 肿瘤的起源目前有体细胞学说和干细胞学说。如果说宇宙起源于大爆炸,那肿瘤则是细胞在人体里的大爆炸。恶性肿瘤是来自干细胞的大爆炸而良性肿瘤是来自体细胞的大爆炸,因为致肿瘤因子既要改变与＂增殖＂相关的基因或基因组,
作者 陈旭东
机构地区 复旦大学上海医学院分子医学教育部重点实验室
出处 《温州医学院学报》 CAS 2012年第1期96-97,100,共3页 Journal of Wenzhou Medical College
关键词 乳腺肿瘤 干细胞 WNT信号通路 转基因小鼠 综述文献
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献20

  • 1Al-Hajj M,Wicha MS,Benito-Hernandez A,et al.Prospec-tive identification of tumorigenic breast cancer cells[J].Proc Natl Acad Sci USA,2003,100(7):3983-3988.
  • 2Gudjonsson T,Villadsen R,Nielsen HL,et al.Isolation,immortalization,and characterization of a human breast epithelial cell line with stem cellProperties[J].Genes Dev,2002,16(6):693-706.
  • 3Dontu G,Abdallah WM,Foley JM,et al.In vitroPropaga-tion and transcriptionalProfiling of human mammary stem/Progenitor cells[J].Genes Dev,2003,17(10):1253-1270.
  • 4Woodward WA,Chen MS,Behbod F,et al.On mammary stem cells[J].J Cell Sci,2005,118(Pt 16):3585-3594.
  • 5Ponti D,Costa A,Zaffaroni N,et al.Isolation and in vitroPropagation of tumorigenic breast cancer cells with stem/Progenitor cellProperties[J].Cancer Res,2005,65(13):5506-5511.
  • 6PolakisP.Wnt signaling and cancer[J].Genes Dev,2000,14 (15):1837-1851.
  • 7Dontu G,Wicha MS.Survival of mammary stem cells in suspension culture:implications for stem cell biology and neoplasia[J].J Mammary Gland Biol Neoplasia,2005,10(1):75-86.
  • 8Howard B,Ashworth A.SignallingPathways implicated in early mammary gland morphogenesis and breast cancer[J].PloS Genet,2006,2(8):e112.
  • 9Liu S,Dontu G,Wicha MS.Mammary stem cells,self-re-newalPathways,and carcinogenesis[J].Breast Cancer Res,2005,7(3):86-95.
  • 10Hiraguri S,Godfrey T,Nakamura H,et al.Mechanisms of inactivation of E-cadherin in breast cancer cell lines[J].Cancer Res,1998,58(9):1972-1977.

二级参考文献28

  • 1McDermott SP, Wicha MS. Targeting breast cancer stem cells [J]. Mole Oncol, 2010, 4(5) :404 -419.
  • 2Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells [ J ]. Proc Natl Acad Sci U S A, 2003, 100 (7) : 3983 - 3988.
  • 3Shipitsin M, Campbell LL, Argani P, et al. Molecular definition of breast tumor heterogeneity [ J ]. Cancer Cell, 2007, 11(3) :259 -273.
  • 4Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome [ J ] . Cell Stem Cell, 2007,1 (5) :555 -567.
  • 5Wright MH, Calcagno AM, Salcido CD, et al. Brcal breast tumors contain distinct CD44 +/CD24 - and CD133 + cells with cancer stem cell characteristics [ J ]. Breast Cancer Res,2008,10(1) :R10.
  • 6Hwang-Verslues WW, Kuo WH, Chang PH, et al. Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers [ J ]. PLoS One, 2009,4(12) :e8377.
  • 7Pece S, Tosoni D, Confalonieri S, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content [J]. Cell, 2010,140(1) :62 - 73.
  • 8Chuthapisith S, Eremin J, El-Sheemey M, et al. Breast cancer chemoresistanee: emerging importance of cancer stem cells[J]. Surg Oncol, 2010, 19 (1) :27 -32.
  • 9Phillips TM, McBride WH, Pajonk F. The response of CD 24 ( - / low ) / CD 44 + breast cancer- initiating cells to radiation[J]. J Natl Cancer Inst, 2006, 98(24) :1777 - 1785.
  • 10Chen MS, Woodward WA, Behbod F, et al. Wnt/beta- catenin mediates radiation resistance of Scal + progenitors in an immortalized mammary gland cell line [ J]. J Cell Sci, 2006,120(3) :468 -477.

共引文献3

同被引文献29

  • 1Gupta PB, Fillmore CM, Jiang G, et al. Stochastic state transitions giverise to phenotypic equilibrium in populations of cancer cells [J] . Cell,2011,146 (4) : 633-644.
  • 2Chiara F, Massimo B, Daniele G, et al. Epithelial mesenchymal transition and breast cancer: Role, molecular mechanisms and clinical im-pact [J] . Cancer Treatment Reviews, 2012, 38 (6) : 689-697.
  • 3AI-Hajj M,Wicha MS, Benito-Hemandez A, et al. Prospective identification of tumorigenic breast cancer cells [J] . Proc Natl Acad SciUSA, 2003,100 (7) : 3983-3988.
  • 4Tanaka H, Nakamura M, Kameda C, et al. The Hedgehog signalingpathway plays an essential role in maintaining the 0044.024. subpopula tion and the side population of breast cancer cells [ J].Anticancer Res, 2009, 29 (6) : 2147-2157.
  • 5Lagadec C, Vlashi E,Della Donna L, et al. Radiation-induced repro-gramming of breast cancer cells [J] . Stem Cells,2012, 30 (5) : 833-844.
  • 6Martello G,Rosato A, Ferrari F, et al. A MicroRNA targeting dicer formetastasis control [J] . Cell, 2010, 141 (7) : 1195-1207.
  • 7Al-Hajj M,Wicha MS,Benito-Hernandez A. Prospective identification of tumorigenic breast cancer cells[J].Proceedings of the National Academy of Sciences(USA),2003,(07):3983-3988.doi:10.1073/pnas.0530291100.
  • 8McDermott SP,Wicha MS. Targeting breast cancer stem cells[J].Molecular 0ncology,2010.404-419.
  • 9Gupta PB,Fillmore CM,Jiang G. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells[J].Cell,2011,(04):633-644.
  • 10Chiara F,Massimo B,Daniele G. Epithelial mesenchymal transition and breast cancer:Role,molecular mechanisms and clinical impact[J].Cancer Treatment Reviews,2012.689697.

引证文献2

二级引证文献3

温州医学院学报
2012年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部