654-2与黄芪联合应用对糖尿病肾病尿微量白蛋白的影响

The clinical effect of urinary micro-albumin of diabetic nephropathy treated with 654-2and astragaulus membranaceus

目的观察654-2与黄芪(astragaulus membranaceus)联合应用对糖尿病肾病(DN)尿微量白蛋白的临床疗效。方法住院糖尿病肾病患者175例,随机分为治疗组(88例)和对照组(87例),两组均用西医常规处理,治疗组同时加用654-2与黄芪,疗程3周,并分别测定两组治疗前后24小时尿白蛋白排出量(UAE)、空腹血糖(FBG)、餐后2小时血糖(P2BG)、糖化血红蛋白(HbA1c)。结果治疗组治疗后UAE有明显改善(P<0.01),且优于对照组(P<0.01)。结论 654-2与黄芪联合应用对糖尿病肾病尿微量白蛋白的治疗有较好的疗效。

Objective To observe the clinical efficacy of a combined treatment using 654-2 and astragaulus membranaceus on Urinary micro-albumin（UMA） of diabetic nephropathy.Methods 175 patients with diabetes nephropathy were randomly divided into treatment group（88 cases） and Control group（87 cases）,both on westerns conventional treatment,simultaneously,add 654-2 and astragaulus membranaceus on Treatment group,and the treated program lasted 3 weeks.Determin UAE、FBG、P2BG、HbA1c on the two groups before and after treatment respectively.Results The UAE of Treatment group has significantly improved after treatment（P0.01）,and better than control group（P0.01）.Conclusion 654-2 and astragaulus membranaceus treated with urinary micro-albumin（UMA） of diabetic nephropathy have a better curative effect.