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白细胞介素-13可溶性受体对支气管哮喘小鼠嗜酸粒细胞凋亡的影响 被引量：4

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摘要 支气管哮喘（简称哮喘）是由多种细胞包括气道炎症细胞、结构细胞和细胞组分参与的气道慢性炎症性疾病…。嗜酸粒细胞（Eos）是哮喘气道炎症的关键效应细胞。哮喘气道Eos凋亡不足或延迟是气道Eos大量浸润的成因之一。
作者 史海广 杨学敏 成家军 李志奎
机构地区 第四军医大学附属西京医院呼吸科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2012年第1期66-68,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
基金 国家自然科学基金（30770926）
关键词 嗜酸粒细胞凋亡 支气管哮喘 哮喘小鼠 白细胞介素-13 可溶性受体 哮喘气道炎症 慢性炎症性疾病 IL-13
分类号 R562.25 [医药卫生—呼吸系统]
  • 相关文献

参考文献10

  • 1支气管哮喘防治指南（支气管哮喘的定义、诊断、治疗和管理方案）[J].中华结核和呼吸杂志,2008,31(3):177-185. 被引量：2518
  • 2王丽丽,魏亚强,蔡累,宋爱玲,王伟华,张英起,李志奎.小鼠白细胞介素-13受体α2胞外区的原核表达与纯化[J].中国生物制品学杂志,2010,23(4):365-368. 被引量：7
  • 3Andrews A,Nasir T,Bucchieri F,et al.IL-13 receptor alpha 2:a regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts.J Allergy Clin Immunol,2006,118:858-865.
  • 4Kasaian M,Donaldson D,Tchistiakova L,et al.Efficacy of IL-13neutralization in a sheep model of experimental asthma. Am J Respir Cell Mol Biol,2007,36:368-376.
  • 5万琪,吴朔,宋爱玲,李运明,张英起,李志奎.可溶性IL-13受体α2对支气管哮喘小鼠气道炎症的影响[J].国际呼吸杂志,2010,30(23):1413-1416. 被引量：2
  • 6Woolley K,Gibson P,Carty K,et al.Eosinophil apoptosis and the resolution of airway inflammation in asthma.Am J Respir Crit Care Med,1996,154:237-243.
  • 7Leick-Maldonado E,Kay F,Leonhardt M,et al.Comparison of glucocorticoid and cysteinyl leukotriene receptor antagonist treatments in an experimental model of chronic airway inflammation in guinea-pigs.Clin Exp Allergy,2004,34:145-152.
  • 8李志奎,李树钧,遆新宇,赵峰,任新玲,张艰,宋立强,王长征,钱桂生.地塞米松对嗜酸性粒细胞凋亡及Fas mRNA表达的影响[J].西北国防医学杂志,2008,29(6):415-418. 被引量：1
  • 9Ganzalo J,Jia G,Aguirre V,et al. Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response.Immunity,1996,4:1-14.
  • 10Kibe A,Inoue H,Fukuyama S,et al.Differential regulation by glucocorticoid of interleukin-13-induced eosinophilia,hyperresponsiveness, and goblet cell hyperplasia in mouse airways.Am J Respir Crit Care Med,2003,167:50-56.

二级参考文献39

  • 1王长征,蒲萍,吴国明,李淑平,郭先健.吸入血小板活化因子对豚鼠气道反应性影响及机制的研究[J].中华结核和呼吸杂志,1995,18(3):155-157. 被引量：20
  • 2Yimin Qin,Sogyong Auh,Lyubov Blokh,Catherine Long,Isabelle Gagnon,Kimm J. Hamann.TNF-α Induces Transient Resistance to Fas-Induced Apoptosis in Eosinophilic Acute Myeloid Leukemia Cells[J].Cellular & Molecular Immunology,2007,4(1):43-52. 被引量：19
  • 3McKenzie AN, Culpepper JA, De Waal Malefyt R, et al. Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc Natl Acad Sci USA,1993,90 (8): 3735- 3739.
  • 4Minty A, Chalon P, Deroeq JM, et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature, 1993, 362(6417): 248-250.
  • 5Zurawski G, De Vries JE. Interleukin 13, an interleukin 4--like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today, 1994, 15( 1 ): 19-26.
  • 6Bousquet J, Jeffery PK, Busse WW, et al. Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med, 2000, 161(5): 1720-1745.
  • 7Kuperman DA, Huang X, Koth LL, et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med, 2002, 8(8): 885-889.
  • 8Aman MJ, Tayebi N, Obiri NI, et al. cDNA cloning and characterization of the human interleukinl3 receptor alpha chain. J Biol Chem, 1996, 271(46): 29265-29270.
  • 9Hilton D J, Zhang JG, Metcalf D, et al. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci USA, 1996, 93 ( 1 ): 497-501.
  • 10Donaldson DD, Whitters MJ, Fitz LJ, et al. The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1. J Immunol, 1998, 161 (5): 2317-2324.

共引文献2524

同被引文献38

  • 1Knosp CA,Carroll HP,Elliott J. SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses[J].Journal of Experimental Medicine,2011,(07):1523-1531.
  • 2Paris D,Beaulieu-Abdelahad D,Abdullah L. Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation[J].European Journal of Pharmacology,2013,(13):145-153.
  • 3Miklossy G,Hilliard TS,Turkson J. Therapeutic modulators of STAT signalling for human diseases[J].Nature Reviews Drug Discovery,2013,(08):611-629.
  • 4Ferreira RC,Freitag DF,Cutler AJ. Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases[J].PLoS Genetics,2013,(04):1553-7390.
  • 5Gong JH,Shin D,Han SY. Blockade of airway inflammation by kaempferol via disturbing tyk-STAT signaling in airway epithelial cells and in asthmatic mice[J].Evidence-based Complementary and Alternative Medicine,2013,(07):1-12.
  • 6Simeone-Penney MC,Severgnini M,Tu P. Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma[J].Journal of Immunology,2007,(10):6191-6199.
  • 7Yang XO,Zhang H,Kim BS. The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation[J].Nature Immunology,2013,(07):732-740.
  • 8Shan L,Redhu NS,Saleh A. Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells:role of MAPKs (ERK1/2,p38,and JNK)and STAT3 pathways[J].Journal of Immunology,2010,(12):7134-7143.
  • 9Zhu L,Hao Y,Guan H. Effect of sinomenine on vascular smooth muscle cell dedifferentiation and neointima formation after vascular injury in mice[J].Molecular and Cellular Biochemistry,2013,(01):53-62.
  • 10Wjst M,Lichtner P,Meitinger T. STAT3 single-nucleotide polymorpbisms and STAT3mutations associated with hyper-IgE syndrome are not responsible for increased serum IgE serum levels in asthma families[J].European Journal of Human Genetics,2009,(03):352-356.

引证文献4

二级引证文献28

中华结核和呼吸杂志
2012年 第1期

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