缺氧诱导脑红蛋白表达及运动生物学应用展望

Neuroglobin expression induced by hypoxia and expectation for its application in sports biology

脑红蛋白(Ngb)是新近发现的神经系统特异的携氧球蛋白,主要在脊椎动物脑组织中高表达,与脑内氧供应密切相关。研究表明,缺氧能够诱导Ngb的表达,而高表达的Ngb能够保护神经元免受缺氧损伤,从而在神经系统缺氧、缺血损伤中具有重要的神经保护功能。从Ngb的生物学特征研究出发,对Ngb在医学中的研究现状做一综述,并对Ngb在体育科学中的应用前景进行展望。

Neuroglobin（Ngb） is a newly discovered particular oxygen carrying globin in the nervous system,mainly expressed in the brain tissues of vertebrates at a high level,closely related to oxygen supply in brains.It is indicated in researches that hypoxia can induce the expression of Ngb,while Ngb expressed at a high level can pro-tect neurons from being damaged by hypoxia,thus it is provided with an important nerve protecting function in nervous system damages caused by hypoxia or ischemia.By studying the biological characteristics of Ngb,the au-thors gave an overview of the current situation of Ngb study in medical science,and expected the application of Ngb in sports science.