我院心血管系统药物不良反应报告分析

ADR case reports of cardiovascular drugs

目的分析该院心血管系统药物不良反应(ADR)的相关因素,为临床合理用药提供参考。方法对该院2004年4月～2011年4月收集并上报于全国药物不良反应监测网络的315例心血管系统药物不良反应报告进行统计分析。结果 315例ADR报表中涉及的药物品种共有47个,其中发生率最高的是降压药;ADR累及皮肤及及其附件损害最多。结论应提高对药品不良反应监测工作重要性的认识,加强临床心血管系统药物合理使用的管理,避免或减少其ADR的发生。

Objective To analyze the adverse drug reactions（ADR） of cardiovas-cular drugs occurring in First people＇s Hospital so as to provide reference for the rational use of medication in clinics.Methods 315 cases of ADR report had been collected,which were reported in national adverse drug reactions monitor network from April 2004 to April 2011 in Hefei First People＇s Hospital.Results 315 ADR cases involved 47 cardiovascular drugs.Among the cardiovascular drugs,antihypertensive drugs accounted for the highest proportion.Skin and its accessories damage accounted for the highest percentage of ADR of cardiovascular drugs.Conclusion We should attach greater importance to ADR monitoring,strengthen the clinical management of the rational use of antibiotics and reduce the incidence of adverse drug reactions.