摘要
目的:探讨以奥美拉唑、克拉霉素为基础的两种三联疗法治疗幽门螺旋杆菌(HP)相关消化性溃疡的效果。方法:将80例HP阳性消化性溃疡患者随机分为治疗组和对照组,治疗组用奥美拉唑、克拉霉素和甲硝唑,对照组用奥美拉唑、克拉霉素和阿莫西林,对两组治疗结果进行比较。结果:两组患者溃疡愈合总有效率均达到95.0%以上,HP完全根除率均达到85.0%,两组差异均没有显著性(P>0.05)。结论:奥美拉唑、克拉霉素和甲硝唑对HP相关消化性溃疡具有良好的疗效,适用于对青霉素过敏的患者,值得在临床推广使用。
Objective：To investigate the effect of two kinds of omeprazole and clarithromycin-based triple therapy in treatment of helicobacter pylori（HP）associated peptic ulcer.Methods：80 patients with HP infected peptic ulcer were randomly divided into treatment group and control group,treatment group used omeprazole,clarithromycin and metronidazole,control group used omeprazole,clarithromycin and amoxicillin,and the treatment results were compared.Results：The total effective rate of ulcer healing of two groups reached 95.0%,HP eradication rate reached 85.0%,the differences were not significant（P0.05）.Conclusion：Using omeprazole,clarithromycin and metronidazole in the treatment of HP-related peptic ulcer has a good effect,suitable for patients allergic to penicillin,and worth for clinical promotion.
出处
《医学理论与实践》
2012年第3期261-262,共2页
The Journal of Medical Theory and Practice
