乳铁蛋白对早期断奶仔猪血清和粪便中金属元素含量及抗氧化性能的影响

Influence of lactoferrin on metal element contents in serum and excrement and antioxidant capacity of early weaned piglets

选用21日龄断奶仔猪96头,根据日粮中乳铁蛋白的添加量250、500、750 mg/kg设置处理,每个处理4个重复,每个重复6头仔猪。试验为期21 d。试验结果:各乳铁蛋白添加组断奶仔猪平均日增重显著提高(P<0.05),腹泻率显著降低(P<0.05),血清中铁含量显著提高(P<0.05);500、750 mg/kg添加组仔猪粪便中铁含量显著降低(P<0.05),粪便中铜、锌、锰含量均低于对照组,且随乳铁蛋白添加量的增加而降低;500 mg/kg添加组的料肉比最低,血清中MDA含量比对照显著降低(P<0.05),SOD活力和GSH-Px活力比对照显著提高(P<0.05)。结果表明:在基础日粮中适量添加乳铁蛋白(500 mg/kg)能在一定程度上提高断奶仔猪的生产性能,提高血清中微量元素的含量,降低粪便中金属元素的含量,提高机体的抗氧化性能。

The experiment was conducted to investigate the effects of supplemental lactoferrin（LF） in basal diet on growth performance,metal element contents in serum and excrement and antioxidant capacity of the weaning piglets.Ninety-six 21-day-old weaning piglets were randomly allocated into 4 treatments with 4 replicates in each treatment,and 6 piglets per replicate.Each treatment was fed with basal diet supplemented with 0,250,500 and 750 mg/kg LF respectively for 21 d.The result showed： basal diets supplemented with LF could significantly improve the daily gain and reduce the diarrhea rate（P0.05）and the treatment fed with diet supplemented with 750 mg/kg LF yielded the best feed/gain ratio;the content of Fe in serum could be significantly increased by LF（P0.05）;the content of Fe in the excrement of the treatments fed with diet supplemented with 500 mg/kg and 750 mg/kg LF could be significantly reduced,and the content of metal Cu,Zn and Mn in other treatments tended to reduce in the excrement（P0.05）.The supplementation of 500 mg/kg LF could significantly decrease the content of MDA in serum（P0.05）and increase the SOD and the GSH-Px activity（P0.05）.The results indicated that supplementation of LF could improve growth performance,increase the contents of trace elements in serum,reduce the contents of metal in excrement and improve the antioxidant capacity of the organism.The appropriate supplemental amount of LF was 500 mg/kg under this experimental condition.