肺通气功能对左室舒张功能不全诊断价值的研究

Diagnostic value of the lung function test for the diastolic heart failure

目的探索肺通气功能对左室舒张功能不全的诊断价值。方法选取左室舒张功能不全患者34例和正常对照组20例,进行肺通气功能检查,采用受试者工作特征曲线ROC分析各项肺通气功能参数对左室舒张功能不全的诊断价值。结果左室舒张功能不全患者中有70.59%存在限制性通气功能障碍,和对照组相比多项肺功能指标FEV1、FEV1占预计值%、FVC、FVC占预计值%、MMEF均显著降低(P<0.05),FEV1占预计值%和FVC占预计值%的ROC曲线下面积较大,分别为0.845和0.880。结论左室舒张功能不全患者的肺通气功能显著降低,肺通气功能检查可帮助左室舒张功能不全的诊断。FVC占预计值%可能是诊断左室舒张功能不全的较好指标。

Objective To explore the diagnostic value of the lung function test （spirometry） for the diastolic heart failure. Methods 34 patients with diastolic heart failure and 20 healthy subjects were included. Main assessments included the lung function test and echoeardiography. Receiver Operator Characteristive Curve （ ROC curve） was used to assess the diagnostic value of the lung function test （spirometry） for the diastolic heart failure. Results A restrictive vcntilatory defect was present in 70. 59 percent of the patients with dias- tolic heart failure presence. Compared with healthy subjects, the lung function parameters such as FEVl , FVC, FEV1% pre, FVC% pre, MMEF were significant decrease in the patients with diastolic heart failure（ P 〈 0.05 ）. The areas under the ROC curve of FEV1% pre and FVC% pre were O. 845 and 0. 880, respectively. Conclusion Patients with diastolic heart failure have significant decrease in lung function. Spirometry may assist in diagnosis of the diastolic heart failure. FVC% pre may he a better index for diagnosis of the diastolic heart failure than others.