变应性鼻炎与支气管哮喘患者的肺功能改变

Analysis of lung function of patients with allergic rhinitis and bronchial asthma

目的通过对变应性鼻炎(A组)与支气管哮喘患者(B组)及健康对照组(C组)进行肺功能检测,寻找两种疾病肺功能改变的意义。方法采用美国Sensor-Medics6200体描箱对A、B、C组患者检测肺功能有关指标。结果 A、B两组V25%、V50%明显降低,与C组比较,差异显著(P<0.01);A组V50%与B组比较,有意义地增高(P<0.05);B组RV明显增高,与A、C组比较,差异显著(P<0.01);A、B两组Raw与C组比较,有意义地增高(P<0.05);FVE1%:B组低于C组(P<0.05),而A组与C组及A组与B组对照均无明显差异(P>0.05);DLCO%:B组高于A及C两组(P<0.05)。结论两组患者对肺功能影响相似,主要是小气道阻塞,只是哮喘组影响强。

Objective To investigste the significance and relationship in pulmonary function between allergic rhinitis and bron- chial asthma. Method Patients with allergic rhinitis, patients with bronchial asthma and the healthy people were enrolled into group A, group B and group C, respectively. The pulmonary function was measured by American Sensor-Medics 6200 physical description box. Re- sults V25% , V50% in group A and B showed lower than those in group C, with significant differences （P 〈 0. 01 ） ; V50% of group A significantly increased, with significant difference compared with group B （P 〈 O. 05 ） ; R~% in group B showed higher than those in group A and C, with significant differences （P 〈 O. 01 ） ; Raw% in group A and B showed much higher than those in group C, with significant differences （ P 〈 O. 05 ） ; FVE1% ： group B was lower than group C （ P 〈 0. 05 ） , while there were no significant differences between group A and group C, and between group A and group B; DLCO% in group B was significantly higher than that in group A and C （P 〈 0. 05 ）. Conclusion The effects of lung functions are similar in two groups and the effect factor is mainly small airway obstructive, which is stron- ger in asthma.