利多卡因胶浆涂抹口腔治疗小儿疱疹性口炎疗效观察

Observation on therapeutic effect of application of Lidocaine Hydrochloride mucilage in the mouth in the treatment children's herpetic stomatitis

目的观察利多卡因胶浆涂抹口腔治疗小儿疱疹性口炎的疗效。方法将疱疹性口炎患者200例随机分为两组:治疗组100例在基础及常规治疗的基础上,加用利多卡因胶浆涂抹口腔;对照组100例应用基础及常规治疗,比较两组疗效。结果治疗组显效82例(82.0%),有效10例(10.0%),总有效率为92.0%;对照组显效51例(51.0%),有效23例(23.0%),总有效率为74.0%;两组比较差异有高度统计学意义(P<0.01)。治疗组无效8例(8.0%),对照无效26例(26.0%),两组比较差异有高度统计学意义(P<0.01)。结论利多卡因胶浆涂抹口腔治疗小儿疱疹性口炎,疗效确切,安全可靠,无明显不良反应,值得临床推广应用。

Objective To observe the therapeutic effect of application of Lidocaine Hydrochloride mucilage in the mouth in the treatment children＇s herpetic stomatitis.Methods 200 patients with herpetic stomatitis were randomly allocated to two groups to see the result.The control group（n=100） received basic routine treatment only,while the treatment group（n=100） also received the treatment of application of Lidocaine Hydrochloride mucilage in the mouth.Results As for the treatment group,82 cases（82.0%） were significantly effective,10 cases（10.0%） were effectual and 8 cases（8.0%） were unfruitful with a total cure rate as 92.0%.When it comes to the control group,51 cases（51.0%） were significantly effective,23 cases（23.0%） were effectual and 26 cases（26.0%） were unfruitful with a total cure rate as 74.0%.There was significant difference in total rate of effects between two groups（P〈 0.01）.Conclusion The treatment of application Lidocaine Hydrochloride mucilage in mouth in treating children＇s herpetic stomatitis is safe and effective,with no obvious side effects,and worthy of being widely used.