不同浓度罗哌卡因等比重腰麻在剖宫产手术中的效果比较

Effect comparison on the different concentrations of isobaric Ropivacaine for lumbar anesthesia in cesarean section

目的比较不同浓度罗哌卡因等比重腰麻在剖宫产术中的麻醉效果。方法将180例行剖宫产手术孕妇随机分为A组、B组及C组,每组各60例,分别给予0.75%、0.50%和0.30%的等比重罗哌卡因进行腰麻,比较三组在剖宫产术中的麻醉效果、感觉运动阻滞情况及不良反应发生率。结果 A组、B组及C组麻醉优良率分别为91.7%、90.0%和56.7%,A、B组显著优于C组(P<0.01),但A、B组之间差异无统计学意义(P>0.05);A组及B组感觉运动阻滞起效时间、痛觉阻滞时间显著优于C组(P<0.05),A组及B组无显著差别(P>0.05);三组感觉阻滞平面比较,差异无统计学意义(P>0.05);A组、B组及C组不良反应发生率分别为16.6%、15.0%和13.4%,三组比较差异无统计学意义(P>0.05)。结论0.5%罗哌卡因等比重腰麻可满足剖宫产手术的要求,具有麻醉起效时间快、不良反应少的特点。

Objective To compare the effect of different concentrations of isobaric Ropivacaine for lumbar anesthesia in cesarean section.Methods 180 cases scheduled for cesarean section were randomly divided into group A（0.75% Ropivacaine）,group B（0.50% Ropivacaine） and group C（0.30% Ropivacaine）,with 60 cases each in group.Anesthetic effect,motor block,sensory block and incidence of adverse reactions were compared among three groups.Results Excellent and good rate were 91.7%,90.0% and 56.7% in group A,group B and group C,of which much higher in group A and group B than group C（P〉 0.01）,but there was no significant difference between group A and group B（P 〈0.05）;the onset time of motor and sensory block and the duration of sensory in group A and group B were shorter than that of group C（P 〈0.05）,and there was no significant difference between group A and group B（P 〉0.05）;there were no significantly difference of incidence of adverse reactions among three groups（16.6% vs 15.0% vs 13.4%）（P〉 0.05）.Conclusion 0.5% isobaric Ropivacaine meets the needs of cesarean section because of faster anesthetic effect time and less adverse reactions.