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脂蛋白相关磷脂酶A_2与冠心病的关系 被引量:6

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摘要 脂蛋白相关磷脂酶A2(LP-PLA2)属于磷脂酶A2超家族,血液循环中的LP-PLA2是冠心病的一个重要的炎症标志物,能够与血液中的血脂结合,其中主要与低密度脂蛋白结合,水解其中的磷脂生成促炎介质,促进炎症反应。近年的研究表明,LP-PLA2与冠心病的发生、发展关系密切,是冠心病的独立预测因子;LP-PLA2特异性高,生物学变异小,可能为临床检测提供新的依据。
出处 《社区医学杂志》 2012年第2期46-48,共3页 Journal Of Community Medicine
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同被引文献57

  • 1孙彦彦,邱春光,韩战营,卢文杰,王卫平,邱承杰,杨长宝,陈晓杰.脂蛋白相关磷脂酶A2与冠状动脉粥样硬化病变程度及斑块稳定性的关系[J].中国实用医刊,2010,37(4):39-41. 被引量:7
  • 2刘文东.冠心病患者血浆P-选择素水平的变化[J].潍坊医学院学报,2005,27(6):435-436. 被引量:3
  • 3江大建,刘霜.急性冠脉综合征患者血清sCD40L与sP-选择素相关性研究[J].山东医药,2006,46(13):35-36. 被引量:4
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