摘要
遗传学的经典原理已为临床医师所熟悉并得到广泛应用；分子遗传学的核心是生命过程中所需要的各种蛋白质由基因决定，并因此决定生命体的表型。随着医学的发展，特别是遗传学和病理生理学的发展，许多临床现象和疾病机制难以用经典的遗传学原理加以解释，如源于分化的成熟体细胞的克隆动物未老先衰；具有相同DNA序列的同卵双生双胞胎在表型和疾病易感性方面表现出明显的差异；组织特异性基因在不同受体、组织的表达不同，以及复杂疾病的发生机制与遗传学理论不一致，等等。
出处
《中华围产医学杂志》
CAS
北大核心
2012年第2期80-84,共5页
Chinese Journal of Perinatal Medicine
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