10681例输血前、术前、产前患者感染性疾病标志物检查结果分析

Analysis of markers of infectious diseases in before transfusion,preoperative and prenatal patients

目的探讨术前、输血前及产前相关经血液传播感染性疾病标志物检测的必要性及其在医院感染控制中的意义。方法采集2010年1～12月所有来院的手术、输血或孕产妇10681例患者的静脉血,运用ELISA方法检测经血传播感染性疾病标志物。结果 10681例患者标本中HBsAg阳性共计573例,阳性率为5.36%,其中以HBsAg+HBeAb+HBcAb模式最多,阳性率为2.76%;HBsAb阳性3346例,阳性率为31.33%。59例抗HCV-IgG阳性,占0.55%。HIV抗体4例初筛阳性,送上级确认实验室进行确认均为阳性。梅毒螺旋体抗体检测ELISA方法共有119例,其中TPPA阳性97例,TRUST阳性12例,且滴度均大于1:8。结论术前、输血前及产前患者血清感染性指标有一定比例的阳性率,因此对术前、输血前或产前患者进行相关经血传播感染性疾病标志物检测,有利于医患双方采取有效的预防措施,同时避免医疗纠纷的发生。

Objective To study the necessity of detecting markers of infectious diseases before transfusion,preoperative and prena- tal and the significance in hospital infection control. Methods The serum samples of 10,681 cases were detected the markers of infectious diseases transmission by blood with ELISA. Results There were 573 HBsAg - positive samples in all samples ,the postive rate was 5.36%, specially the model of HBsAg ＋ HBeAb ＋ HBcAb was most of all, it＇s rate was 2. 76%. There were 3346 HBsAb - positive samples in all samples, the postive rate was 3 1. 33%. And 59 anti - HCV - IgG positive samples in all samples （0. 55% ）. The screen test of HIV antibody was executed. There were 4 positive in all cases and all were confirmed by HIV confirmatory laboratory. Conclusion There is a certain pro- portion of positive rate in the samples of before transfusion, preoperative and prenatal patients, so it is necessary to detect markers of infectious diseases before transfusion, preoperative and prenatal patients.