子宫肌瘤患者的中医体质特征研究

Traditional Chinese Medicine constitution of patients with uterine fibroid

目的基于中医的体质分类学说，探索体检人群中发现的子宫肌瘤患者的体质特征。方法选择413例体检人群中的子宫肌瘤患者作为病例组，选择同期413例非子宫肌瘤女性体检者作为对照组，按照病例一对照研究设计进行流行病学调查，应用《中医体质问卷》进行体质辨识；同时采用《女性月经情况调查表》调查月经的相关信息，从健康体检的问诊信息中提取既往病史信息。计算相关指标的频数和百分数，组间的比较用方差分析。率和构成比的比较用卡方检验，配对资料计算OR值和95％的可信区间。结果子宫肌瘤组气郁质的发生率高于非子宫肌瘤组（X2=8．209，P〈0．05）。实性体质（痰湿质、湿热质、气郁质及血瘀质）的子宫肌瘤患者与月经有关的症状发生率升高，差异有统计学意义；既往疾病中高血压的发生率高于对照组。结论气郁质是子宫肌瘤的常见偏颇体质。实性体质是子宫肌瘤患者体质改变的主要倾向。

Objective To explore the constitution characteristics of patients with uterine fibroids. Methods A total of 413 patients with uterine fibroids （ patient group） and 413 healthy women （control group） were enrolled in this case-control study. All the participants were required to fill in a questionnaire on Chinese Medicine constitution. The frequency and percentage of indicators were calculated, and analysis of variance and Chi-square test were used to find difference between the two groups. Results The incidence of Qi-stagnation constitution in the patient group was higher than that in the control group （X2 = 8. 209, P 〈 0. 05 ） . The incidence of menstrual abnormalities was increased in patients with constitution of Phlegm-dampness and Dampness-heat, Qi-stagnation and Blood-stasis. The detection rate of hypertension of the patient group was also significantly increased. Conclusion The most common constitution of patients with uterine fibroid is Qi-stagnation.