缺血性脑血管病中血糖异常与临床预后的分析

Analysis of the abnormal glucose and clinical prognosis of transient ischemic attack

目的探讨血糖异常在缺血性脑血管病患者预后判定中的意义。方法选取2006年10月～2011年10月笔者所在医院收治的454例脑血管病患者,根据预后情况分为脑梗死组(276例)和TIA组(178例),检测其空腹及餐后2h血糖、糖化血红蛋白等生化指标,测患者血压及体重指数,并对空腹血糖>6.0mmol/L的患者行糖耐量试验,分析各组患者中血糖异常情况。结果在454例急性脑缺血性脑血管病患者中,合并血糖异常200例。脑梗死组和TIA组患者血糖异常的比例具有显著差异(P<0.01);脑梗死组患者糖尿病患病率显著高于TIA组(P<0.05)。结论脑血管病患者其糖代谢状态在判断患者预后中具有重要价值,行积极有效的降糖治疗可能使患者的预后改善。

Objective To explore glucose in patients with ischemic cerebrovascular disease in determining prognosis significance.Methods Selected the patients from October 2006 to October 2011 in our hospital 454 cases with cerebrovascular disease,cerebral infarction were divided into groups according to prognosis（276 cases） and the TIA group（178 cases）,to detect the fasting and postprandial 2 h blood glucose,glycated hemoglobin and other biochemical indicators,and measured blood pressure and body mass index,and fasting blood glucose 6.0 mmol/L in patients with oral glucose tolerance test,analyzing of the group of patients with blood glucose abnormalities.Results In 454 cases of acute ischemic cerebrovascular disease,the combined glucose 200 cases.Cerebral infarction and TIA patients with acute ischemic cerebrovascular disease with the incidence of significant differences（P0.01）;the prevalence of diabetes in patients with cerebral infarction was significantly higher than the TIA group（P0.05）.Conclusion The glucose metabolism in patients with cerebrovascular disease in determining the prognosis of patients in the state of great value,the line active and effective hypoglycemic therapy may improve the prognosis of patients.